Pulmonary Hamartoma Initially Misdiagnosed As Adenocarcinoma: A Case Report and Review of the Literature

Pulmonary Hamartoma Initially Misdiagnosed As Adenocarcinoma: A Case Report and Review of the Literature Publisher

Hosseini E ; Farahani MM ; Sami R ; Shadmehr MB

Source: Respirology Case Reports Published:2025

Abstract

Pulmonary hamartomas are common benign lung tumours that rarely present with hemoptysis and may mimic malignancy. We report a 39-year-old non-smoker with 2 months of hemoptysis and a 3-cm right upper-lobe lesion. CT-guided core biopsy with IHC suggested adenocarcinoma (CK7, TTF-1, Napsin-A positive), but PET-CT showed no metastasis. The patient underwent VATS resection and final histopathology confirmed pulmonary hamartoma. Symptoms resolved postoperatively with no recurrence at 6-month follow-up. This case highlights potential false-positive biopsy/IHC results from entrapped benign epithelium and the role of surgical excision for definitive diagnosis. © 2025 The Author(s). Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology.

Style	Citing Format
MLA	Hosseini E, et al.. "Pulmonary Hamartoma Initially Misdiagnosed As Adenocarcinoma: A Case Report and Review of the Literature." Respirology Case Reports, vol. 13, no. 12, 2025, pp. -.
APA	Hosseini E, Farahani MM, Sami R, Shadmehr MB (2025). Pulmonary Hamartoma Initially Misdiagnosed As Adenocarcinoma: A Case Report and Review of the Literature. Respirology Case Reports, 13(12), -.
Chicago	Hosseini E, Farahani MM, Sami R, Shadmehr MB. "Pulmonary Hamartoma Initially Misdiagnosed As Adenocarcinoma: A Case Report and Review of the Literature." Respirology Case Reports 13, no. 12 (2025): -.
Harvard	Hosseini E et al. (2025) 'Pulmonary Hamartoma Initially Misdiagnosed As Adenocarcinoma: A Case Report and Review of the Literature', Respirology Case Reports, 13(12), pp. -.
Vancouver	Hosseini E, Farahani MM, Sami R, Shadmehr MB. Pulmonary Hamartoma Initially Misdiagnosed As Adenocarcinoma: A Case Report and Review of the Literature. Respirology Case Reports. 2025;13(12):-.
BibTex	@article{ author = {Hosseini E and Farahani MM and Sami R and Shadmehr MB}, title = {Pulmonary Hamartoma Initially Misdiagnosed As Adenocarcinoma: A Case Report and Review of the Literature}, journal = {Respirology Case Reports}, volume = {13}, number = {12}, pages = {-}, year = {2025} }
RIS	TY - JOUR AU - Hosseini E AU - Farahani MM AU - Sami R AU - Shadmehr MB TI - Pulmonary Hamartoma Initially Misdiagnosed As Adenocarcinoma: A Case Report and Review of the Literature JO - Respirology Case Reports VL - 13 IS - 12 SP - EP - PY - 2025 ER -

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