Correlation of N-Terminal Pro-B-Type Natriuretic Peptide Levels and Cardiac Magnetic Resonance Imaging T2∗ in Patients With Β-Thalassaemia Major

Correlation of N-Terminal Pro-B-Type Natriuretic Peptide Levels and Cardiac Magnetic Resonance Imaging T2∗ in Patients With Β-Thalassaemia Major Publisher

Mehrzad V¹ ; Khajouei AS² ; Fahami E³

Source: Blood Transfusion Published:2016

Abstract

Background. Cardiac death secondary to myocardial iron toxicity occurs in 50% of patients with transfusion-dependent β-thalassaemia major. N-terminal pro-B-type natriuretic peptide (NT-proBNP) seems to be a useful tool for early detection of cardiac haemosiderosis. We designed this study to determine whether plasma NT-proBNP levels are predictive of cardiac iron concentration, based on heart T2∗ assessment by magnetic resonance imaging (MRI). Materials and methods. We evaluated plasma NT-proBNP levels in 50 patients with β-thalassaemia major, aged 18 to 46 years, with preserved left ventricular systolic function, all of whom had undergone cardiac MRI within 3 months before the study. Next, three groups were defined based on heart T2∗ value as: group A, patients without evidence of cardiac iron overload (T2∗>20 ms); group B, patients with mild to moderate cardiac iron overload (10 ms

Style	Citing Format
MLA	Mehrzad V, Khajouei AS, Fahami E. "Correlation of N-Terminal Pro-B-Type Natriuretic Peptide Levels and Cardiac Magnetic Resonance Imaging T2∗ in Patients With Β-Thalassaemia Major." Blood Transfusion, vol. 14, no. 6, 2016, pp. 516-520.
APA	Mehrzad V, Khajouei AS, Fahami E (2016). Correlation of N-Terminal Pro-B-Type Natriuretic Peptide Levels and Cardiac Magnetic Resonance Imaging T2∗ in Patients With Β-Thalassaemia Major. Blood Transfusion, 14(6), 516-520.
Chicago	Mehrzad V, Khajouei AS, Fahami E. "Correlation of N-Terminal Pro-B-Type Natriuretic Peptide Levels and Cardiac Magnetic Resonance Imaging T2∗ in Patients With Β-Thalassaemia Major." Blood Transfusion 14, no. 6 (2016): 516-520.
Harvard	Mehrzad V, Khajouei AS, Fahami E (2016) 'Correlation of N-Terminal Pro-B-Type Natriuretic Peptide Levels and Cardiac Magnetic Resonance Imaging T2∗ in Patients With Β-Thalassaemia Major', Blood Transfusion, 14(6), pp. 516-520.
Vancouver	Mehrzad V, Khajouei AS, Fahami E. Correlation of N-Terminal Pro-B-Type Natriuretic Peptide Levels and Cardiac Magnetic Resonance Imaging T2∗ in Patients With Β-Thalassaemia Major. Blood Transfusion. 2016;14(6):516-520.
BibTex	@article{ author = {Mehrzad V and Khajouei AS and Fahami E}, title = {Correlation of N-Terminal Pro-B-Type Natriuretic Peptide Levels and Cardiac Magnetic Resonance Imaging T2∗ in Patients With Β-Thalassaemia Major}, journal = {Blood Transfusion}, volume = {14}, number = {6}, pages = {516-520}, year = {2016} }
RIS	TY - JOUR AU - Mehrzad V AU - Khajouei AS AU - Fahami E TI - Correlation of N-Terminal Pro-B-Type Natriuretic Peptide Levels and Cardiac Magnetic Resonance Imaging T2∗ in Patients With Β-Thalassaemia Major JO - Blood Transfusion VL - 14 IS - 6 SP - 516 EP - 520 PY - 2016 ER -

Science Communicator Platform

Authors

Abstract