A Rare Presentation of Primary Cardiac Myxofibrosarcoma: Case Report and Literature Review Publisher Pubmed



Soltani S¹ ; Garousi M¹ ; Mirzaee E¹ ; Koolaji S² ; Nazari H³ ; Emami S⁴ ; Zare Mehrjardi A⁵ ; Arefpour AM¹ Show Affiliations
Source: Cancer Reports Published:2024

Abstract

Background: Primary cardiac myxofibrosarcoma is a rare and aggressive malignancy, with the majority of approaching strategies relying on case reports. This article provides insights into its diagnosis and treatment. Case Presentation: This paper presents the case of a 40-year-old man with sudden onset hemoptysis, leading to the diagnosis of primary cardiac myxofibrosarcoma. Treatment involved open-heart surgery to excise the left atrium tumor, followed by 6 cycles of adjuvant chemotherapy. Unfortunately, brain metastasis developed, leading to the patient's death 1 year after initial diagnosis. Conclusion: Primary cardiac myxofibrosarcoma remains a clinical challenge with an unfavorable prognosis. Early diagnosis through advanced imaging is crucial, and research is needed to explore innovative treatments. This case underscores the complexities of managing this rare cardiac malignancy and highlights the necessity for ongoing investigations to enhance patient outcomes. © 2024 The Authors. Cancer Reports published by Wiley Periodicals LLC.