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Co-Occurrence of Multiple Sclerosis and Thomsen’S Myotonia: A Report of Two Cases Publisher Pubmed



Ashtari F1 ; Bahreini SA2 ; Zahednasab H3
Authors
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Authors Affiliations
  1. 1. Department of Neurology, Isfahan Neurological Sciences Research Center, Isfahan Medical Education Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, United States
  3. 3. Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran

Source: Functional Neurology Published:2014


Abstract

Multiple sclerosis (MS) is a common demyelinating disease of the central nervous system in which an abnormal immune system response results in damage to the myelin sheaths surrounding nerves. The etiology of MS remains elusive, although it has been suggested to be influenced by both genetic and environmental factors. Here, we report two exceptional cases of patients affected by both MS and Thomsen’s myotonia. Electromyography and MRI scans confirmed the presence of both diseases in the referred cases. Although the mechanisms underlying the co-occurrence of MS and Thomsen’s disease are unclear, we have endeavored to offer plausible explanations for it. © 2014, CIC Edizioni Internazionali s.r.l. All rights reserved.
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