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Platelet-Rich Plasma (Prp) Therapy in Skin Rejuvenation: Benefits and Adverse Influences



Nekooiemarnany N1 ; Jaffary F2 ; Nilforoushzadeh MA1
Authors
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Authors Affiliations
  1. 1. Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Skin Diseases and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan AND Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, Iran

Source: Journal of Isfahan Medical School Published:2015

Abstract

A safe and effective rejuvenation method with few side effects is one of the main purposes of most of the aesthetic procedures. As wound healing process is similar to rejuvenation mechanisms, diverse methods such as ablative and non-ablative laser have been applied to meet this target. A recent method that has remarkably taken experts' and technicians’ attention is platelet-rich plasma (PRP) injection. This article reviews molecular mechanisms of aging and rejuvenation. It also evaluates clinical documents regarding the effects of platelet-rich plasma in rejuvenation beside its possible side effects. Because of high concentration of growth factors in platelet-rich plasma, it potentially can accelerate wound healing. However, there is a concern about the relation between the high level of growth factors and induction of signaling cascades of tumors. Long-term platelet-rich plasma outcomes need to be more investigated in cohort studies. © 2015 Isfahan University of Medical Sciences(IUMS). All rights reserved.
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