Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Diagnostic Accuracy of Ultrasonography for Detection of Intussusception in Children; a Systematic Review and Meta-Analysis Publisher



Rahmani E1 ; Amanibeni R2 ; Hekmatnia Y3 ; Yaseri AF4 ; Ahadiat SA5 ; Boroujeni PT6 ; Kiani M7 ; Tavakoli R2 ; Shafagh SG8 ; Shirazinia M9 ; Garousi S9 ; Arzaghi M10 ; Benam SP11 ; Rigi A12 Show All Authors
Authors
  1. Rahmani E1
  2. Amanibeni R2
  3. Hekmatnia Y3
  4. Yaseri AF4
  5. Ahadiat SA5
  6. Boroujeni PT6
  7. Kiani M7
  8. Tavakoli R2
  9. Shafagh SG8
  10. Shirazinia M9
  11. Garousi S9
  12. Arzaghi M10
  13. Benam SP11
  14. Rigi A12
  15. Salmani A13
  16. Abdollahi Z14
  17. Rokni FK15
  18. Nikbakht T16
  19. Abadi SAH15
  20. Roohinezhad R8
  21. Haririan Y18
  22. Darouei B2
  23. Fayyazishishavan E19
  24. Farrokhi M22
Show Affiliations
Authors Affiliations
  1. 1. School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. School of Medicine, Isfahan University ofMedical Sciences, Isfahan, Iran
  3. 3. Islamic Azad University ofMedical Science, Mazandaran, Sari, Iran
  4. 4. School of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran
  5. 5. The Advocate Center for Clinical Research, Ayatollah Yasrebi Hospital, Kashan, Iran
  6. 6. Advanced Diagnostic Interventional Radiology Research Center, Tehran University ofMedical Science, Tehran, Iran
  7. 7. School of Medicine, Zanjan University ofMedical Sciences, Zanjan, Iran
  8. 8. Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran
  9. 9. Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
  10. 10. Shahid Beheshti University ofMedical Sciences, Tehran, Iran
  11. 11. Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran
  12. 12. Islamic Azad University, Zahedan Branch, Zahedan, Iran
  13. 13. Mechanical Engineering, Sharif University of Technology, Tehran, Iran
  14. 14. Department of Radiology, School ofMedicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
  15. 15. Faculty of Medical Sciences, Islamic Azad University of Chalus, Mazandaran, Chalus, Iran
  16. 16. Islamic Azad University, Tehran Medical Branch, Tehran, Iran
  17. 17. School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
  18. 18. School of Medicine, Shiraz university of Medical Sciences, Shiraz, Iran
  19. 19. Department of Biostatistics and Data Science, School of Public Health, The University of Texas Health Science Center at Houston (UTHealth), Houston, 77030, TX, United States
  20. 20. Harvard Medical School, Boston, MA, United States
  21. 21. Division of Endocrinology, Diabetes, Hypertension, Brigham and Women’s Hospital, Boston, MA, United States
  22. 22. ERIS Research Institute, Tehran, Iran

Source: Archives of Academic Emergency Medicine Published:2023


Abstract

Introduction: The diagnosis of intussusception can be challenging in children due to the fact that the findings of clinical evaluations are nonspecific and most of the patients present with unclear history. Therefore, in this systematic review and meta-analysis, we aimed to investigate the diagnostic accuracy of ultrasonography for detection of intussusception and also compare the efficacy of point-of-care ultrasound (POCUS) with radiologist-performed ultrasound (RADUS). Methods: Two independent reviewers systematically searched different online electronic databases including MEDLINE, Scopus, Web of Science, Google Scholar, Embase, and Cochrane from inception to December 1, 2022 to identify published papers reporting accuracy of ultrasonography for diagnosis of intussusception. The quality assessment of the included studies was investigated using the Quality Assessment of Diagnostic Accuracy Studies (QUADAS)-2 tool. Results: A total of 1446 records were retrieved in the initial search of databases. After screening the titles, a total of 344 studies were retrieved for the detailed assessment of full-text. Finally, 37 studies were included in qualitative and quantitative analysis. The pooled sensitivity and specificity of ultrasonography for diagnosis of intussusception were 0.96 (95% CI: 0.95-0.97) and 0.97 (95% CI: 0.97-0.98), respectively. The pooled positive likelihood ratio (PLR) and negative likelihood ratio (NLR) were 24.57 (95% CI: 8.26-73.03) and 0.05 (95% CI: 0.04-0.08), respectively. The area under the hierarchical summary receiver operating characteristic (HSROC) curve was 0.989. Mete-regression showed that there is no significant difference between diagnostic performance of POCUS and RADUS (p = 0.06 and rDOR (diagnostic odds ratio) = 4.38 (95% CI: 0.92-20.89)). Conclusion: This meta-analysis shows that ultrasonography has excellent sensitivity, specificity, and accuracy for diagnosis of intussusception in pediatric patients. Moreover, we found that diagnostic performance of POCUS is similar to that of RADUS for diagnosis of intussusception. © 2023, Archives of Academic Emergency Medicine. All Rights Reserved.
Related Docs
1. The Diagnostic Value of Abdominal Ultrasound in the Primary Diagnosis of Intussusception in Clinically Suspected Children, Journal of Isfahan Medical School (2012)
2. Diagnostic Accuracy Ofultrasonography for Identification of Elbow Fractures in Children; a Systematic Review and Meta-Analysis, Archives of Academic Emergency Medicine (2023)
3. Predicting Factors of Reducibility of Invagination With Barium Enema in Children, Journal of Isfahan Medical School (2011)
4. Diagnostic Accuracy of Ultrasonography for Diagnosis of Elbow Fractures in Children, European Journal of Trauma and Emergency Surgery (2022)
5. Diagnostic Performance of Ultrasonography for Identification of Small Bowel Obstruction; a Systematic, Archives of Academic Emergency Medicine (2024)
Experts (# of related papers)
View all Related Experts
Atoosa Adibi (1)
Reza Azizkhani (1)