Successful En-Bloc Kidney Transplantation From a 5-Year-Old Donor With Cerebral Palsy to a 60-Year Old Recipient: A Case Report Publisher



Khorrami MH¹ ; Dehghani S^{2, 3} ; Mashhadi R⁴ ; Abdi H⁴ ; Namdari F³ Show Affiliations
Source: Translational Research in Urology Published:2021

Abstract

Introduction There are a growing number of unmet kidney donor sources. So, alternative donor sources, such as donation after circulatory determination of death (DCDD), are taken into the consideration. Case presentation In this study, we represent successful En-Bloc kidney transplantation from a 4-year-Old donor with cerebral palsy to a 60-year old recipient. The kidney of a 4-year-old boy with congenital CP (weight=12Kg; BMI=12) with brain death was transplanted to a 60-year-old man (weight =70Kg; BMI=23.6). Panel-reactive antibody (PRA) to HLA class I (PRA I) and HLA class II (PRA II) were observed less than 5% in the 60-year old recipient. Also, the PRA titer with complement-dependent cytotoxicity (PRA-CDC) and the donor-recipient WBC crossmatch was negative. Our case is reported by a successful EKBT to an adult with the en-bloc kidney of a 4-year-old child with cerebral palsy. The small kidneys of a cerebral palsy child are adapting and functioning well in the adult body. Conclusions Therefore, CP pediatric donors can be good resources for transplantation whenever available. © 2021 Urology Research Center (URC).