Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Increased Β-Globulin Fractions of the Serum Proteins in Rabbit Experimental Autoimmune Myasthenia Gravis



Messripour M1 ; Torabinia D1
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Clinical Biochemistry, Faculty of Pharmacy, Isfahan Medical Sciences University, Isfahan, Iran

Source: Acta Cardiomiologica Published:1996

Abstract

Rabbit experimental autoimmune myasthenia gravis (EAMG) has been produced and the relationship of the pattern of serum protein electrophoresis, anti-AChR titers and clinical muscle weakness in individual animals were studied. The responses of the animals to the immunizations with rat leg muscle acetylcholine receptor (AChR) were significantly different. The muscle weakness did not correlate with the titer of anti-AChR antibody produced in the individual rabbits. However, during the course of immunizations, a relationship was seen between the onset of the animal muscle weakness and β-globulin fractions of the serum proteins as examined by electrophoresis. The data suggest that the concentration of the serum β- globulin may be taken as a clinical parameter to evaluate prognosis of myasthenia gravis.
Related Docs
1. Indirect Quenching Fluororeceptor Assay of Anti-Achr Antibodies, Molecular and Chemical Neuropathology (1997)
2. Increased Proportion of Tc17 and Th17 Cells and Their Significant Reduction After Thymectomy May Be Related to Disease Progression in Myasthenia Gravis, NeuroImmunoModulation (2018)
3. Myasthenia Gravis and Covid-19: A Systematic Review and Meta-Analysis, Basic and Clinical Neuroscience (2024)
4. Is Myasthenia Gravis a Real Complication of the Covid-19 Vaccine? a Case Report-Based Systematic Review, Canadian Journal of Infectious Diseases and Medical Microbiology (2022)
Experts (# of related papers)
View all Related Experts
Vahid Shaygannejad (2)
Nafiseh Esmaeil (1)