Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Fractional Co2 Laser As an Effective Modality in Treatment of Striae Alba in Skin Types Iii and Iv



Fateminaeini F1 ; Soghrati M2 ; Nilforuoshzadeh MA3
Authors
Show Affiliations
Authors Affiliations
  1. 1. Skin Disease and Leishmaniasis Research Center, Department of Dermatology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Skin Diseases and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, Iran

Source: Journal of Isfahan Medical School Published:2014

Abstract

Background: Rapid stretching of the skin over the weak connective tissue leads to development of striae distensae. Recently, researchers have shown special interest towards use of fractional photothermolysis in treatment of striae and several studies have shown its usefulness. We aimed to assess the efficacy of Fractional CO2 laser in treatment of striae alba. Methods: A randomized clinical trial was carried out in 6 women with striae alba. Ninety two striae were randomly divided into two groups. Five sessions of laser resurfacing were performed in group 1, every 2-4 weeks. Group 2 was treated with 10% glycolic acid and 0.05% tretinoin cream nightly. Photographs were taken from the striae before and two weeks after the end of the treatment. Mean surface area of striae compared between two groups. Patients' views regarding the degree of improvement were assessed via visual analogue scale (VAS). Findings: Mean difference of striae surface area was significantly more after treatment in group 1 (-37.1 ± 15.6 cm2) in comparison with group 2 (-7.9 ± 9.0 cm2) (P < 0.001). Mean VAS was significantly higher in group 1 (3.05 ± 0.74) compared to group 2 (0.63 ± 0.66) (P < 0.001). Conclusion: Fractional photothermolysis via Fractional CO2 laser seems to be an effective method for treatment of striae alba.
Related Docs
View other Related Docs
1. Fractional Co2 Laser As an Effective Modality in Treatment of Striae Alba in Skin Types Iii and Iv, Journal of Research in Medical Sciences (2012)
2. Promising Option for Treatment of Striae Alba: Fractionated Microneedle Radiofrequency in Combination With Fractional Carbon Dioxide Laser, Dermatology Research and Practice (2016)
3. Systematic Review of Single and Combined Treatments for Different Types of Striae: A Comparison of Striae Treatments, Journal of the European Academy of Dermatology and Venereology (2021)
4. Combination of Hydroquinone and Fractional Co2 Laser Versus Hydroquinone Monotherapy in Melasma Treatment: A Randomized, Single-Blinded, Split-Face Clinical Trial, Indian Journal of Dermatology (2019)
5. Comparison of Fractional Carbon Dioxide Laser Alone and in Combination With Subcision in Improving Atrophic Acne Scars, Journal of Isfahan Medical School (2013)
6. Comparison of Q-Switched 1064-Nm Nd: Yag Laser and Fractional Co2 Laser Efficacies on Improvement of Atrophic Facial Acne Scar, Journal of Research in Medical Sciences (2011)
7. Repigmentation of Hypopigmented Scars Using Combination of Fractionated Carbon Dioxide Laser With Topical Latanoprost Vs. Fractionated Carbon Dioxide Laser Alone, Indian Journal of Dermatology (2015)
8. Efficacy of Punch Elevation Combined With Fractional Carbon Dioxide Laser Resurfacing in Facial Atrophic Acne Scarring: A Randomized Split-Face Clinical Study, Indian Journal of Dermatology (2015)
Experts (# of related papers)
View all Related Experts
Gita Faghihi (11)
Ali Asilian (11)
Other Related Docs
9. Evaluation of the Efficacy of Piroxicam Gel in the Control of Pain and Erythema Caused by Fractional Co2 Laser Compared With Lubricant Gel, Journal of Isfahan Medical School (2011)
10. A Comparative Study on the Usefulness of Fractional Co 2 and Fractional Er:Yag in Acne Scars: A Split-Face Trial, Advanced Biomedical Research (2023)
11. Low Level Laser Therapy for the Treatment of Chronic Wound: Clinical Considerations, Biomedical and Pharmacology Journal (2015)
12. Combination of Q-Switched Nd: Yag and Fractional Erbium: Yag Lasers in Treatment of Melasma: A Randomized Controlled Clinical Trial, Journal of Lasers in Medical Sciences (2017)
13. The Comparison Between Trichloroacetic Acid 50% and Co2 Laser in the Treatment of Cutaneous Leishmaniasis Scar, Indian Journal of Dermatology (2011)
14. Comparative Study of the Efficacy of Co2 and Fraxel Lasers in Treatment of Cutaneous Leishmaniasis Scars, Journal of Isfahan Medical School (2014)
15. A Comparative Study of the Use of a 980 Nm Diode Laser and 10600Nm Co2 in the Treatment of Gingival Melanin Pigmentation, Journal of Lasers in Medical Sciences (2024)
16. Systemic Isotretinoin Therapy and Central Macular and Choroidal Thicknesses in Acne Vulgaris: Is There Any Association?, Cutaneous and Ocular Toxicology (2023)
17. Comparing the Efficacy and Patient Satisfaction in Treatment of Facial Static Wrinkles Using Co2 Fraxel Laser Alone or With Radiofrequency, Journal of Isfahan Medical School (2014)
18. Efficacy of Autologous Platelet-Rich Plasma Combined With Fractional Ablative Carbon Dioxide Resurfacing Laser in Treatment of Facial Atrophic Acne Scars: A Split-Face Randomized Clinical Trial, Indian Journal of Dermatology, Venereology and Leprology (2016)
19. Comparison Between 1% Tretinoin Peeling Versus 70% Glycolic Acid Peeling in the Treatment of Female Patients With Melasma, Journal of Drugs in Dermatology (2011)
20. A Comparison Between the Effects of Glucantime, Topical Trichloroacetic Acid 50% Plus Glucantime, and Fractional Laser Plus Glucantime on Cutaneous Leishmaniasis Lesions, Journal of Isfahan Medical School (2013)
21. Combination of Continuous Wave Co2 Laser and Topical Application of Trichloroacetic Acid 50% Vs Co2 Laser Alone the Treatment of Cutaneous Leishmaniasis (A Case Series of 6 Patients), Journal of Cosmetic Dermatology (2020)
22. Systematic Review and Meta-Analysis of Randomized Clinical Trials Comparing Efficacy, Safety, and Satisfaction Between Ablative and Non-Ablative Lasers in Facial and Hand Rejuvenation/Resurfacing, Lasers in Medical Science (2022)
23. A Comparison Between the Effects of Glucantime, Topical Trichloroacetic Acid 50% Plus Glucantime, and Fractional Carbon Dioxide Laser Plus Glucantime on Cutaneous Leishmaniasis Lesions, Dermatology Research and Practice (2016)
24. New Combination of Triamcinolone, 5-Fluorouracil, and Pulsed-Dye Laser for the Treatment of Keloid Andhypertrophic Scars, Journal of Isfahan Medical School (2012)
25. Comparing the Effects of Conventional Method, Pulse Dye Laser and Erbium Laser for the Treatment of Hypertrophic Scars in Iranian Patients, Journal of Research in Medical Sciences (2007)
26. Potential Emerging Treatment in Vitiligo Using Er:Yag in Combination With 5Fu and Clobetasol, Journal of Cosmetic Dermatology (2018)
27. Q-Switched Frequency-Doubled Nd:Yag (532 Nm) Laser Versus Trichloroacetic Acid 35% Peeling in the Treatment of Dorsal Hand Solar Lentigo: An Assessor-Blind Split-Hand Randomized Controlled Trial, Journal of Cosmetic Dermatology (2022)
28. Carbon Dioxide Laser for the Treatment of Lupoid Cutaneous Leishmaniasis (Lcl): A Case Series of 24 Patients, Dermatology Online Journal (2006)
29. The Effectiveness of a 5% Retinoic Acid Peel Combined With Microdermabrasion for Facial Photoaging: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial, Dermatology Research and Practice (2017)
30. Fractional Erbium:Yag Laser (2940 Nm) Plus Topical Hydroquinone Compared to Intradermal Tranexamic Acid Plus Topical Hydroquinone for the Treatment of Refractory Melasma: A Randomized Controlled Trial, Journal of Dermatological Treatment (2022)
31. The Effect of Intralesional Triamcinolone Versus Combination of Intralesional Triamcinolone With Co2 Fraxel Laser in Treatment of Patients With Hypertrophic Scars, Journal of Isfahan Medical School (2013)
32. Evaluation of Co2 Laser Efficacy in the Treatment of Cutaneous Leishmaniasis, International Journal of Dermatology (2004)
33. New Combination of Triamcinolone, 5-Fluorouracil, and Pulsed-Dye Laser for Treatment of Keloid and Hypertrophic Scars, Dermatologic Surgery (2006)
34. Application of Laser for Treatment of Cutaneous Leishmaniasis: A Review of Literature, Lasers in Medical Science (2020)