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Longitudinally Extensive Transverse Myelitis As a Sign of Multisystem Inflammatory Syndrome Following Covid-19 Infection: A Pediatric Case Report Publisher Pubmed



Pourmoghaddas Z1 ; Sadeghizadeh A2 ; Tara SZ3 ; Zandifar A4 ; Rahimi H1 ; Saleh R5 ; Ghazavi M6 ; Yaghini O6 ; Hosseini N6 ; Javadi N7 ; Saadatnia M8 ; Vossough A4
Authors

Source: Journal of Neuroimmunology Published:2021


Abstract

COVID-19 infection can cause inflammatory reactions that could involve several organs. In the pediatric population, Multi-System Inflammatory Syndrome in Children (MIS-C) has been reported as one of the consequences of COVID-19. We report a unique pediatric COVID-19 patient with MIS-C, associated with paralysis of the extremities. MRI showed abnormal signal in the cervical spinal cord compatible with transverse myelitis. Methylprednisolone and IVIG were administered, without significant symptom improvement. As a next step, Infliximab was tried for her, and she responded remarkably well to this treatment. Infliximab may be considered as a treatment option in COVID-19 patients with transverse myelitis. © 2021 Elsevier B.V.