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Manipulating Measurement Scales in Medical Statistical Analysis and Data Mining: A Review of Methodologies



Marateb HR1 ; Mansourian M2 ; Adibi P3 ; Farina D4
Authors
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Authors Affiliations
  1. 1. Department of Biomedical Engineering, The University of Isfahan, Isfahan, Iran
  2. 2. Department of Biostatistics and Epidemiology, Health School, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran
  4. 4. Universitatsmedizin Gottingen, Georg-August-Universitat, Department of Neurorehabilitation Engineering, Bernstein Focus Neurotechnology Gottingen, Bernstein Center for Computational Neuroscience, Gottingen, Germany

Source: Journal of Research in Medical Sciences Published:2014

Abstract

Background: selecting the correct statistical test and data mining method depends highly on the measurement scale of data, type of variables, and purpose of the analysis. Different measurement scales are studied in details and statistical comparison, modeling, and data mining methods are studied based upon using several medical examples. We have presented two ordinal-variables clustering examples, as more challenging variable in analysis, using Wisconsin Breast Cancer Data (WBCD). Ordinal-to-Interval scale conversion example: a breast cancer database of nine 10-level ordinal variables for 683 patients was analyzed by two ordinal-scale clustering methods. The performance of the clustering methods was assessed by comparison with the gold standard groups of malignant and benign cases that had been identified by clinical tests. Results: the sensitivity and accuracy of the two clustering methods were 98% and 96%, respectively. Their specificity was comparable. Conclusion: by using appropriate clustering algorithm based on the measurement scale of the variables in the study, high performance is granted. Moreover, descriptive and inferential statistics in addition to modeling approach must be selected based on the scale of the variables.