Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Efficacy and Side-Effects of Megestrol Acetate Tablets on Postpone Menstruation Compared With Low-Dose Estrogen Combined Oral Contraceptives (Ld)



Allameh T1 ; Allameh Z1 ; Moatamedy F2
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Obstetrics and Gynecology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Journal of Isfahan Medical School Published:2013

Abstract

Background: Women's menstrual suppression is desired for many reasons. Menstrual suppresion, especially during the holidays, trips, camps, military exercises, special events, academic examinations or athletic events is desirable. This study, with emphasis on safety of megestrol acetate tablets, aimed to determine the effect of this tablet on retardation of menstruation compared with low-dose estrogen combined oral contraceptives (LD). Methods: In this clinical-trial study, 140 applicants to postpone menstruation left for pilgrimage randomly devided to two groups, LD and megestrol acetate recipients. Data were collected through a researcher-made questionnaire and were analyzed by Mann-Whitney U and chi-square tests. Findings: The frequency of individuals reported symptoms such as headache or dizziness (P < 0.05), nausea or vomiting (P < 0.05), changes in appetite (P < 0.05) and changes in sexual desire (P < 0.05), was significantly more in the LD recipients compared with megestrol acetates. Conclusion: Megestrol acetate can be seen as a drug with the same efficacy of LD, but safer than it, to postpone the menstruation.
Related Docs
View other Related Docs
1. Herbal Treatment of Oligomenorrhea With Sesamum Indicum L.: A Randomized Controlled Trial, Galen Medical Journal (2016)
2. The Effect of Testosterone Gel on Fertility Outcomes in Women With a Poor Response in in Vitro Fertilization Cycles: A Pilot Randomized Clinical Trial, Journal of Research in Medical Sciences (2018)
3. Frequency Distribution and Associated Factors of Menopausal Symptoms in Women in Isfahan, Iran, Journal of Isfahan Medical School (2013)
4. Nephroprotective Effect of Estrogen and Progesterone Combination on Cisplatin-Induced Nephrotoxicity in Ovariectomized Female Rats, Indian Journal of Nephrology (2016)
5. The Effect of Chamomile on Menstruation Pattern and Serum Androgens in Polycystic Ovary Syndrome, Medicinal Plants (2022)
6. Determinants of Satisfaction From Depot Medroxyprogesterone Acetate, Cyclofem, and Low Dose Contraceptive Pills: A Descriptive Study on Health Centers in Iran, Journal of Isfahan Medical School (2012)
7. Effects of Pomegranate Supplement on Menopausal Symptoms and Quality of Life in Menopausal Women: A Double-Blind Randomized Placebo-Controlled Trial, Complementary Therapies in Clinical Practice (2022)
8. Use of Combined Oral Contraceptives: Retrospective Study in Isfahan, Islamic Republic of Iran, Eastern Mediterranean Health Journal (2006)
Experts (# of related papers)
View all Related Experts
Hatav GhasemiTehrani (3)
Elham Naghshineh (2)
Other Related Docs
9. Effect of Soy Isoflavones Supplementation on Migraine Characteristics, Mental Status and Calcitonin Gene-Related Peptide (Cgrp) Levels in Women With Migraine: Results of Randomised Controlled Trial, Nutrition Journal (2022)
10. Does Oral Contraceptive Use Increase the Risk of Future Cardiovascular Events? Results From the Isfahan Cohort Study, Iranian Heart Journal (2016)
11. The Effects of Lavender Aromatherapy on Menopausal Symptoms: A Single-Blind Randomized Placebo-Controlled Clinical Trial, International Journal of Pharmaceutical Research (2018)
12. Assessment of Reasons for Discontinuation of Different Methods of Contraception, Journal of Medical Sciences (2006)
13. Evaluating the Effects of Vitamin D and Vitamin E Supplement on Premenstrual Syndrome: A Randomized, Double-Blind, Controlled Trial, Iranian Journal of Nursing and Midwifery Research (2016)
14. Comparing the Effects of Low-Dose Contraceptive Pills to Control Dysfunctional Uterine Bleeding by Oral and Vaginal Methods, Pakistan Journal of Medical Sciences (2013)
15. Effect of Calcium and Vitamin B1 on the Severity of Premenstrual Syndrome: A Randomized Control Trial, International Journal of Pharmacy and Technology (2016)
16. Evaluation of the Effect of Letrozole in the Ovarian Hyperstimulation Syndrome Prevention in Participants at Risk of Treatment With Ovulation-Stimulating Drugs: A Randomized Controlled Trial, Reports of Biochemistry and Molecular Biology (2022)
17. Oral Contraceptive Misuse As a Risk Factor for Cerebral Venous and Sinus Thrombosis, Journal of Research in Medical Sciences (2012)
18. Saffron for the Management of Premenstrual Dysphoric Disorder: A Randomized Controlled Trial, Advanced Biomedical Research (2020)
19. The Effect of Low-Dose Combined Oral Contraceptive Pills on Brachial Artery Endothelial Function and Common Carotid Artery Intima-Media Thickness, Journal of Stroke and Cerebrovascular Diseases (2014)
20. Function and Sexual Satisfaction of Women Treated With Two Types of Ovulation Stimulant Drugs: Clomiphene and Letrozole, Iranian Journal of Obstetrics, Gynecology and Infertility (2021)