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The Effect of Supplementation With Conjugated Linoleic Acid on Body Composition



Sheykhi M1 ; Azadbakht L2
Authors
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Authors Affiliations
  1. 1. Department of Public Health in Nutrition, Zahedan University of Medical Sciences, Zahedan, Iran
  2. 2. Food Security Research Center and Department of Community Nutrition, School of Nutrition and Food Sciences, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Journal of Isfahan Medical School Published:2014

Abstract

Background: Conjugated linoleic acid (CLA) is defined as isomers of linoleic acid group (18:2), which is an essential fatty acid. It seems that conjugated linoleic acid supplementation reduces body weight and fat mass. The aim of the present study was to investigate the effect of supplementation with conjugated linoleic acid on body composition. Methods: We used PubMed and SID search engine to find articles which were contained the following keywords: Conjugated linoleic acid, Body composition, Adipose tissue, Lean Body mass, BMI, Obesity, Weight retention, and Free fatty acid. After the search, 22 articles were recruited and reviewed. Findings: Several studies showed that supplementation of conjugated linoleic acid reduced body weight and fat mass in the short term in humans and long-term effects of this supplementation on body composition were inconsistent. Previous studies were diverted on body composition, dosage of conjugated linoleic acid, the period of the study, participants, physical activity, body mass index (normal, overweight and obesity in different degrees), age group, number of participants, capsule acceptance, and type of the conjugated linoleic acid isomers. It seemed that c12, t10 isomer caused a better change in body composition. Conclusion: The results of clinical studies on the effects of conjugated linoleic acid on weight and body composition are inconsistent. For see better effect of supplementation with conjugated linoleic acid on body composition, long-term studies are needed. © 2014, Isfahan University of Medical Sciences(IUMS). All rights reserved.
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