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Fulminant Neuromyelitis Optica Spectrum Disorder (Nmosd) Following Covid-19 Vaccination: A Need for Reconsideration? Publisher Pubmed



Motahharynia A1, 2 ; Naghavi S1, 2, 3 ; Shaygannejad V1, 2, 3 ; Adibi I1, 2, 3
Authors
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Authors Affiliations
  1. 1. Center for Translational Neuroscience, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Isfahan Neuroscience Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Department of Neurology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Multiple Sclerosis and Related Disorders Published:2022


Abstract

During the coronavirus disease 2019 (COVID-19) pandemic, mass vaccination was a beneficial strategy in many countries. Nevertheless, reports of serious complications such as postvaccination neuromyelitis optica spectrum disorder (NMOSD) raised concerns about the safety of vaccines. Anamnart and colleagues explained postvaccination NMOSD following different vaccines, including COVID-19. To emphasize the message of this article, in this letter, we present a unique case of postvaccination NMOSD with a fulminant and fatal course, which may show a plausible relationship between COVID-19 vaccination and triggering anti-aquaporin-4 antibody (AQP4-Ab). © 2022
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