Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia in a Young Man With Hypoxia: A Case Report and Review of the Literature Publisher Pubmed



Sami R¹ ; Mahzoni P¹ ; Rezaei M¹ Show Affiliations
Source: Acta Biomedica Published:2019

Abstract

Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) is a rare lung disease, which usually affects older women. This disease is often asymptomatic. For patients who are symptomatic, symptoms usually include cough and dyspnea. In this paper, we reported a 38-year-old man who suffered from chest pain for 3 months. CT scan findings revealed scattered nodules that were less than 1 cm. Spirometry was normal and the arterial oxygen saturation at room air was 85%. Open lung biopsy revealed DIPNECH. Patients with DIPNECH are mainly elderly women with symptoms including cough and dyspnea. However, we reported a young man with chest pain and hypoxia without dyspnea. DIPNECH can occur in male and female individuals at any age. (www.actabiomedica.it). © Mattioli 1885.