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Interferon Α-Induced Lupus-Like Reaction in a Mycosis Fungoides Patient: A Case Report Publisher Pubmed



Fatemi Naeini F1 ; Yazdanpanah M1 ; Mohaghegh F1 ; Rajabi P2 ; Tabatabaei ET1
Authors
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Authors Affiliations
  1. 1. Department of Dermatology, Skin Disease and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Department of Pathology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Source: International Journal of Clinical Pharmacology and Therapeutics Published:2022


Abstract

Mycosis fungoides (MF) is the most common form of cutaneous T-cell lymphomas and interferon α is one of the treatment modalities for MF patients. So far, various side effects have been reported in connection with interferon use, including lupus-like reaction, which is relatively rare and classified as an injection-site reactions (ISR). We report a 38-year-old female with history of MF for 2 years who developed cutaneous lesions at the sites of interferon α-2b injections. There are few reports of lupus-like reaction due to therapy with interferon in malignant melanoma and multiple sclerosis (MS) patients, but there is no report in the literature about this side effect among patients with MF. ©2022 Dustri-Verlag Dr. K. Feistle.