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Coexistence of Type B Insulin Resistance and Chronic Inflammatory Demyelinating Polyneuropathy (Cidp) in Type 2 Diabetes Mellitus: Various Manifestations With the Same Pathophysiologic Base? Publisher



Heidarpour M1 ; Aria A2 ; Javadi N3 ; Siavash M1 ; Vakhshoori M4 ; Shafie D4
Authors
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Authors Affiliations
  1. 1. Isfahan Endocrine and Metabolism Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Department of Internal Medicine, Alzahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Student Research Committee, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  4. 4. Heart Failure Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Clinical Medicine Insights: Case Reports Published:2022


Abstract

Chronic inflammatory demyelinating polyneuropathy (CIDP) is a rarely reported disease. The association between diabetes mellitus (DM) and CIDP has been a matter of controversy. Here we presented a 59-year old male patient with uncontrolled type 2 DM presented with simultaneous type B insulin resistance (TBIRS) and CIDP. Both blood glucose and neurological manifestations responded well to corticosteroid therapies. Although the pathogenesis of CIDP remains to be elucidated, the role of antibodies in the pathogenesis of TBIRS and CIDP might be a promising platform for further studies to provide additional insights into the origin of these 2 rare complications. © The Author(s) 2022.
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