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Covid-19-Associated Coagulopathy: A Concise Review on Pathogenesis and Clinical Implications Pubmed



Montazerin SM1 ; Najafi H1 ; Shojaei F1 ; Chi G1 ; Goudarzi S1 ; Sharfaei S2 ; Kahe F1 ; Hassanzadeh S3
Authors
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Authors Affiliations
  1. 1. Division of Cardiovascular Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, 02215, MA, United States
  2. 2. Baim Institute for Clinical Research, Boston, 02215, MA, United States
  3. 3. Acquired Immunodeficiency Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Infezioni in Medicina Published:2021


Abstract

In this review, we summarize the possible mechanisms of COVID-19-associated coagulopathy and compare its features to other similar conditions. The recent CO-VID-19 pandemic has caused enormous mortality and morbidity worldwide. It is important to note that CO-VID-19-associated thrombotic events play a huge role in the morbidity of this disease. Interestingly, it has been observed that this complication may occur de-spite prophylactic anticoagulant therapy. Recent stud-ies on COVID-19-associated coagulopathy revealed that the COVID-19-associated hypercoagulability is more frequently observed among those with a severe course of the disease. Various mechanisms have been suggested as explanations for this condition and possible underlying etiologies. © 2021, EDIMES Edizioni Medico Scientifiche. All rights reserved.
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