Diffuse Lamellar Keratitis After Kerato-Refractive Lenticule Extraction: A Case Report and Systematic Review of Published Cases; [Keratite Lamellaire Diffuse Apres Extraction De Lenticule Kerato-Refractive Rapport De Cas Et Revue Systematique Des Cas Publies] Publisher Pubmed

Summary: Can rapid treatment resolve inflammation after laser eye surgery? A case report describes corneal recovery after steroids and interface washout for a rare complication. #EyeSurgery #Cornea

Pourazizi M ; Nourbakhsh S A ; Peyman A ; Pourmahdi Boroujeni M ; Khalilian M S
Source: Journal Francais d'Ophtalmologie Published:2026

Abstract

Purpose This paper aims to present a rare case of diffuse lamellar keratitis (DLK) following kerato-refractive lenticule extraction (KLEx) surgery and to provide a comprehensive review of all reported cases. Methods In this case report, we present a 27-year-old patient who developed stage 3 DLK following KLEx surgery by SmartSight. The condition was managed with an interface washout using balanced salt solution and an intensive topical corticosteroid regimen. Additionally, we conducted a systematic review of published cases of KLEx-related DLK up to June 2025. Results Clinical symptoms and slit-lamp findings showed significant improvement three days after the interface washout. By day six, the cornea appeared clear with resolution of the inflammation. Conclusion KLEx-related DLK is a rare complication that usually presents within 1–2 days postoperatively, with common symptoms such as blurred vision and ocular discomfort. Management strategies, including topical corticosteroids and interface washout in selected cases, can lead to favorable visual outcomes. © 2025 Elsevier Masson SAS.