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Comparative Study on Cost and Effects of Non Invasive Helicobacter Pylori Diagnostic Tests



Kazemi S1 ; Daghaghzadeh H2 ; Kazemi Y3 ; Habibzadeh M4 ; Moinzadeh F1 ; Davari M5 ; Tavakkoli H2 ; Emami MH2
Authors
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Authors Affiliations
  1. 1. Department of Internal Medicine, School of Medicine And Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Department of Internal Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Department of Speech Therapy, School of Rehabilitation Sciences, Isfahan University of Medical Sciences, Isfahan, Iran
  4. 4. Department of Anesthesiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  5. 5. Department of Clinical Pharmacy and Pharmacy Practice, Health Management and Economics Research Center, School of Management and Medical Information, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Journal of Isfahan Medical School Published:2011

Abstract

Background: Helicobacter pylori is the most common microorganism which colonizes in gastrointestinal system. There are different methods for diagnosis of infection such as rapid stool antigen, urea breath and serology tests. The purpose of this study was comparing the cost and effectiveness of these methods. Methods: 94 dyspeptic patients with mean age of 46 ± 14 years, were evaluated. The patients were considered infected when the results of 2 tests (rapid stool antigen test, urea breath test, rapid urease test and histology) was positive. Findings: Accuracy of rapid stool antigen test was 91%, urea breath test was 82% and serology was 52%. Conclusion: As the cost of stool antigen test was minimum, it is concluded that rapid stool antigen test is more cost-benefit, accurate and reliable test for diagnosis of helicobacter pylori compared with urea breath test and serology. © 2011, Isfahan University of Medical Sciences(IUMS). All rights reserved.
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