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The Effect of Phototherapy With Blue Light in Treatment Acne Vulgaris in Compare With Conventional Therapy With Tetracycline



Faghihi G1 ; Vali A1 ; Bank NS2 ; Ahmadieh E2
Authors
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Authors Affiliations
  1. 1. Department of Dermatology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Journal of Isfahan Medical School Published:2011

Abstract

Background: Acne Vulgaris is a common inflammatory disease of pilosebaceous follicles that affect about 90 percent of the adolescents. Phototherapy has been suggested as an alternative treatment for acne. Phototherapy with blue light (wavelength 405-420 nm) is one of these methods with a good therapeutic effect on inflammatory acne lesions. In this study, the effect of treatment of acne by phototherapy with blue light was compared with conventional tetracycline treatments. Methods: This was a prospective clinical trial study on patients with mild to moderate acne vulgaris. Patients were randomly devided in two groups of 44 subjects (phototherapy or standard treatment). Patients in both groups were followed every 4 weeks to 12 weeks. Type and number of lesions and acne severity index (ASI) were studied before starting the study, during treatment and at each visit. The data were analyzed by Student-t and chi-square test. Finding: The mean age of patients in both groups did not differ significantly. The incidence of comedones, papules, pustules and the mean of acne severity index in reference group that received standard therapy were significantly less than the phototherapy group. Conclusion: This study showed that the effect of phototherapy on comedones is less than inflammatory lesions that may occur because of antibacterial effect of phototherapy with blue light on Propionibacterium acnes. Based on the results, the neonatal phototherapy lamps is not appropriate to obtain a therapeutic effect on acne vulgaris. © 2011, Isfahan University of Medical Sciences(IUMS). All rights reserved.
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