Oral Mandibular Peripheral Osteoma: A Case Report Publisher



Khozeimeh F ; Karami F ; Amirzadeiranaq MH ; Ahmadi S
Source: Journal of Craniomaxillofacial Research Published:2026

Abstract

Peripheral osteomas of the mandible are rare, benign osteogenic tumors characterized by slow-growing cortical or cancellous bone proliferation. This report presents a case of a peripheral osteoma in the mandibular angle and reviews potential etiological factors. A 72-year-old woman presented with a painless, asymptomatic mandibular bone asymmetry and was referred to the oral and maxillofacial department of Isfahan University of Medical Sciences with no visible asymmetric changes in facial soft tissue. The lesion was a 4 cm pedunculated radiopaque mass located on the buccal surface of the left posterior mandible, as confirmed by computed tomography. Surgical ex-cision revealed histopathological features characteristic of lamellar bone admixed with some woven bone, consistent with a diagnosis of peripheral osteoma. Postoperative recovery was smooth, and there was no evidence of recurrence at 1-year follow-up. Peripheral osteomas frequently occur in the mandible and can lead to functional disruptions or cosmetic concerns. Trauma and chronic muscle tension can contribute to their formation, but many cases arise without a clear cause. Typ-ically asymptomatic, surgical removal is the most effective treatment with low recurrence rates. A thorough radiographic assessment is essential; more research is needed to understand their molecular mechanisms. © 2026 Tehran University of Medical Sciences.