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Diagnostic Value of Chest Computed Tomography Scan for Identification of Foreign Body Aspiration in Children: A Systematic Review and Meta-Analysis Publisher



Goodarzy B1 ; Rahmani E2 ; Farrokhi M3 ; Tavakoli R4 ; Fard AM5 ; Ghaleh MR5 ; Yazdi YG5 ; Beni RA6 ; Ghadirzadeh E7 ; Afrazeh F5 ; Khabir YA8 ; Khabir SA8 ; Bakhtiyari P5 ; Atighi J9 Show All Authors
Authors
  1. Goodarzy B1
  2. Rahmani E2
  3. Farrokhi M3
  4. Tavakoli R4
  5. Fard AM5
  6. Ghaleh MR5
  7. Yazdi YG5
  8. Beni RA6
  9. Ghadirzadeh E7
  10. Afrazeh F5
  11. Khabir YA8
  12. Khabir SA8
  13. Bakhtiyari P5
  14. Atighi J9
  15. Mahjoubi M10
  16. Momeni Z5
  17. Jalayeri H1
  18. Hosseini MH11
  19. Hoorshad B5
  20. Tavakoli M5
  21. Seifi S5
  22. Momeni H5
  23. Mirbolook A5
  24. Jobani AE12
  25. Visroudi MM5
  26. Najafi A13
  27. Hosseini Z5
  28. Aboulhassanzadeh S14
  29. Ajami N5
  30. Ramezani S15
  31. Manavi MS5
  32. Safdari S16
  33. Fallahian A5
  34. Azimi H17
  35. Zahedpasha R18
  36. Ranjbar E2
  37. Kahrizi MS7
  38. Lahijan LZ19, 20
Show Affiliations
Authors Affiliations
  1. 1. School of Medicine, Iran University of Medical Sciences, Tehran, Iran
  2. 2. School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Student Research Committee, Department of Epidemiology, School of Public Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  4. 4. Department of Radiology, Arak University of Medical Sciences, Arak, Iran
  5. 5. ERIS Research Institute, Tehran, Iran
  6. 6. School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  7. 7. School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
  8. 8. Graduated, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran
  9. 9. School of Dentistry, Qazvin University of Medical Sciences, Qazvin, Iran
  10. 10. Clinical Research Development Center, Islamic Azad University, Najafabad Branch, Najafabad, Iran
  11. 11. School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  12. 12. Computer Department, Istanbul Aydin University, Istanbul, Turkey
  13. 13. Department of psychology, South Tehran Branch, Islamic Azad University, Tehran, Iran
  14. 14. School of Biotechnology Faculty of Science and Health, Dublin City University, Dublin, Ireland
  15. 15. Department of Orthodontics, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran
  16. 16. Student Research Committee, Dezful University of Medical Sciences, Dezful, Iran
  17. 17. School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
  18. 18. Department of Radiology, School of Medicine, 5th Azar Hospital, Golestan, Gorgan, Iran
  19. 19. Alborz University of Medical Sciences, Alborz, Karaj, Iran
  20. 20. University of Tabriz, Tabriz, Iran

Source: Archives of Academic Emergency Medicine Published:2025


Abstract

Introduction: Foreign body aspiration (FBA) is a common, life-threatening pediatric emergency and was shown to be associated with high risk of morbidity and mortality. This systematic review and meta-analysis aimed to investigate the diagnostic value of chest computed tomography (CT) scan for identification of FBA in children. Methods: From inception to May 2024, a systematic search was carried out across multiple databases including Medline, Scopus, and Web of Science, considering published papers in English language. Quality assessment of the included studies was performed using seven domains of Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). Results: The systematic literature search yielded 7203 articles. The pooled sensitivity and specificity of chest CT scan for identification of FBA were 0.99 (95% CI: 0.98–0.99) and 0.97 (95% CI: 0.96–0.98), respectively. The pooled positive likelihood ratio was 10.12 (95% CI: 4.59–22.20), and pooled negative likelihood ratio was 0.05 (95% CI: 0.02–0.1). Furthermore, the area under the summarized receiver operating characteristic (SROC) curve was 0.98. Conclusions: Our meta-analysis revealed that despite high heterogeneity, in the diagnostic characteristics of chest CT scan among studies, it has high diagnostic value in identifying FBA in suspected pediatric cases. © (2025), (Shaheed Beheshti University of Medical Sciences and Health Services). All rights reserved.
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