Olanzapine Versus Haloperidol: Which Can Control Stuttering Better?

Olanzapine Versus Haloperidol: Which Can Control Stuttering Better?

Shaygannejad V¹ ; Khatoonabadi SAR² ; Shafiei B³ ; Ghasemi M¹ ; Fatehi F⁴ ; Meamar R⁵ ; Dehghani L⁶

Show Affiliations

1. Department of Neurology, Isfahan Neurosciences Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
2. Department of Speech Therapy, Tehran University of Medical Sciences, Tehran, Iran
3. Department of Speech Therapy, Isfahan University of Medical Sciences, Isfahan, Iran
4. Department of Neurology, Tehran University of Medical Sciences, Tehran, Iran
5. Isfahan Neurosciences Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
6. Department of Medical Sciences, Najafabad Branch, Islamic Azad University, Isfahan, Iran

Source: International Journal of Preventive Medicine Published:2013

Abstract

Background: The aim of this study was to compare the effects of olanzapine versus haloperidol to control the signs and symptoms of stuttering. Methods: Ninety-three patients were recruited in a 12-week single-blind randomized clinical trial, which was held between October 2009 and October 2010. Forty-three patients received olanzapine (5 mg/day) and 50 patients, haloperidol (2.5 mg/day). Before and after the study, they were evaluated by a speech pathologist by Van Riper`s questionnaire. The data were analyzed using the SPSS version 16. T-test was used to compare the data between the two groups. Results: Mean of stuttering score (SD) before treatment was 4.67 (0.81) and 4.40 (1.14) in haloperidol and olanzapine groups, respectively (P > 0.05). After treatment, the mean (SD) score was 2.87 (1.32) and 1.56 (0.71) in haloperidol and olanzapine groups, respectively (P = 0.000). Conclusions: It seems that olanzapine does have better impact in controlling stuttering, and it may be recommended to prescribe olanzapine for stutters as the first choice to control the stuttering under a careful follow-up. © 2013 Isfahan University of Medical Sciences(IUMS). All rights reserved.

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Style	Citing Format
MLA	Shaygannejad V, et al.. "Olanzapine Versus Haloperidol: Which Can Control Stuttering Better?." International Journal of Preventive Medicine, vol. 4, no. , 2013, pp. S270-S273.
APA	Shaygannejad V, Khatoonabadi SAR, Shafiei B, Ghasemi M, Fatehi F, Meamar R, Dehghani L (2013). Olanzapine Versus Haloperidol: Which Can Control Stuttering Better?. International Journal of Preventive Medicine, 4(), S270-S273.
Chicago	Shaygannejad V, Khatoonabadi SAR, Shafiei B, Ghasemi M, Fatehi F, Meamar R, Dehghani L. "Olanzapine Versus Haloperidol: Which Can Control Stuttering Better?." International Journal of Preventive Medicine 4, no. (2013): S270-S273.
Harvard	Shaygannejad V et al. (2013) 'Olanzapine Versus Haloperidol: Which Can Control Stuttering Better?', International Journal of Preventive Medicine, 4(), pp. S270-S273.
Vancouver	Shaygannejad V, Khatoonabadi SAR, Shafiei B, Ghasemi M, Fatehi F, Meamar R, et al.. Olanzapine Versus Haloperidol: Which Can Control Stuttering Better?. International Journal of Preventive Medicine. 2013;4():S270-S273.
BibTex	@article{ author = {Shaygannejad V and Khatoonabadi SAR and Shafiei B and Ghasemi M and Fatehi F and Meamar R and Dehghani L}, title = {Olanzapine Versus Haloperidol: Which Can Control Stuttering Better?}, journal = {International Journal of Preventive Medicine}, volume = {4}, number = {}, pages = {S270-S273}, year = {2013} }
RIS	TY - JOUR AU - Shaygannejad V AU - Khatoonabadi SAR AU - Shafiei B AU - Ghasemi M AU - Fatehi F AU - Meamar R AU - Dehghani L TI - Olanzapine Versus Haloperidol: Which Can Control Stuttering Better? JO - International Journal of Preventive Medicine VL - 4 IS - SP - S270 EP - S273 PY - 2013 ER -

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