Comaprative Binding Study of Aluminum and Chromium to Human Transferrin

Comaprative Binding Study of Aluminum and Chromium to Human Transferrin - Effect of Iron Publisher Pubmed

Moshtaghie AA¹ ; Ani M¹ ; Bazrafshan MR¹

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1. Department of Biochemistry, School of Pharmacy, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Biological Trace Element Research Published:1992

Abstract

The characteristics of aluminum and chromium binding to apotransferrin (apo-tf) have been investigated and compared. Both metal ions were taken up by human transferrin forming complexes with the maximum absorbances at 405 nm for chromium-transferrin (cr-tf) and 240 nm for aluminum-transferrin (Al-tf). In the presence of citric acid, chromium binding to transferrin is five times more than aluminum. The binding of aluminum or chromium to apo-transferrin was reduced by 18 and 22% in the presence of 200 ng/mL of iron. The binding of both metals to apo-tf appears to be pH dependent. In acidic pHs, less chromium and more aluminum binding occurred. © 1992 Humana Press Inc.

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Style	Citing Format
MLA	Moshtaghie AA, Ani M, Bazrafshan MR. "Comaprative Binding Study of Aluminum and Chromium to Human Transferrin - Effect of Iron." Biological Trace Element Research, vol. 32, no. 1-3, 1992, pp. 39-46.
APA	Moshtaghie AA, Ani M, Bazrafshan MR (1992). Comaprative Binding Study of Aluminum and Chromium to Human Transferrin - Effect of Iron. Biological Trace Element Research, 32(1-3), 39-46.
Chicago	Moshtaghie AA, Ani M, Bazrafshan MR. "Comaprative Binding Study of Aluminum and Chromium to Human Transferrin - Effect of Iron." Biological Trace Element Research 32, no. 1-3 (1992): 39-46.
Harvard	Moshtaghie AA, Ani M, Bazrafshan MR (1992) 'Comaprative Binding Study of Aluminum and Chromium to Human Transferrin - Effect of Iron', Biological Trace Element Research, 32(1-3), pp. 39-46.
Vancouver	Moshtaghie AA, Ani M, Bazrafshan MR. Comaprative Binding Study of Aluminum and Chromium to Human Transferrin - Effect of Iron. Biological Trace Element Research. 1992;32(1-3):39-46.
BibTex	@article{ author = {Moshtaghie AA and Ani M and Bazrafshan MR}, title = {Comaprative Binding Study of Aluminum and Chromium to Human Transferrin - Effect of Iron}, journal = {Biological Trace Element Research}, volume = {32}, number = {1-3}, pages = {39-46}, year = {1992} }
RIS	TY - JOUR AU - Moshtaghie AA AU - Ani M AU - Bazrafshan MR TI - Comaprative Binding Study of Aluminum and Chromium to Human Transferrin - Effect of Iron JO - Biological Trace Element Research VL - 32 IS - 1-3 SP - 39 EP - 46 PY - 1992 ER -

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