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A Literature Review on the Efficacy and Safety of Botulinum Toxin: An Injection in Post-Stroke Spasticity



Ghasemi M1 ; Salari M1 ; Khorvash F1 ; Shaygannejad V1
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Authors Affiliations
  1. 1. Department of Neurology, Isfahan Neurosciences Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

Source: International Journal of Preventive Medicine Published:2013

Abstract

Background: A variety of techniques for the management of spasticity have been suggested, including positioning, cryotherapy, splinting and casting, biofeedback, electrical stimulation, and medical management by pharmacological agents, Botulinum toxin A (BTA) is now the pharmacological treatment of choice in focal spasticity. BTA by blocking acetylcholine release at neuromuscular junctions accounts for its therapeutic action to relieve spasticity. Methods: A computerized search of Pub Med was carried out to find the latest result about efficacy of BTA in management of post stroke spasticity. Result: Among 84 articles were found, frothy of them included in this review and divided to lower and upper extremity. Conclusions: BTA is a treatment choice in reducing tone and managing post stroke spasticity. © 2013, Isfahan University of Medical Sciences(IUMS). All rights reserved.
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