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Food Allergy Among Iranian Children With Inflammatory Bowel Disease: A Preliminary Report Publisher



Imanzadeh F1 ; Nasri P1 ; Sadeghi S2 ; Sayyari A1 ; Dara N1 ; Abdollah K3 ; Nilipoor Y4 ; Mansuri M5 ; Khatami K1 ; Rouhani P1 ; Olang B1
Authors
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Authors Affiliations
  1. 1. Department of Pediatric Gastroentrology and Hepatology, Mofid Children’s Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  2. 2. Department of Internal Medicine, Al-Zahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Pediatric Infections Research Center, Shahid Beheshti University of Medical Sciences, Iran
  4. 4. Department of Pediatric Pathology Shahid Beheshti University of Medical Sciences, Iran
  5. 5. Department of Pediatric Immunology, Mofid Children’s Hospital, Shahid Beheshti University of Medical Sciences, Iran

Source: Journal of Research in Medical Sciences Published:2015


Abstract

Background: Evidence has shown a link between allergic disease and inflammatory bowel diseases (IBDs). We investigated food allergy in Iranian pediatric IBD patients. Materials and Methods: A cross-sectional study was conducted on a consecutive sample of children with newly diagnosed IBD referring to Mofid Children’s University Hospital in Tehran (Iran) between November 2013 and March 2015. Data on age, gender, history of cow’s milk allergy (CMA), IBD type, routine laboratory tests, and colonoscopic and histopathological findings were gathered. Food allergy was assessed with the skin prick test (SPT). Results: A total of 28 patients including 19 ulcerative colitis (UC), 7 Cronh’s disease (CD), and two with unclassified colitis with a mean age of 8.3 ± 4.4 years. (57.1% females, 42.9% were studied. History of CMA was present in eight patients (28.6%). Seventeen patients (60.7%) had at least one food allergy (68.4% of UC vs. 42.9% of CD, P = 0.230). Ten patients (35.7%) had multiple food allergies (36.8% of UC vs. 42.9% of CD, P > 0.999). Common allergic foods were cow’s milk (28.6%), beef, seafood, albumen, wheat, and walnuts (each 10.7%), and peanuts and chestnuts (each 7.1%). The SPT showed CMA in 68.4% (8/17) of UC but none of the CD patients (P = 0.077). Conclusion: Food allergy is frequent in Iranian pediatric IBD patients with CMA being the most common observed allergy. The CMA seems to be more frequent in UC than in CD patients. © 2015 Journal of Research in Medical Sciences.
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