Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Impact of Positive Family History on the Survival of Breast Cancer in Iran Publisher



Makarian F1 ; Ramezani MA2 ; Ansari L3 ; Makarian S3
Authors
Show Affiliations
Authors Affiliations
  1. 1. Division of Hematology and Oncology, Department of Internal Medicine, Isfahan Medical Sciences University, Isfahan, Iran
  2. 2. Department of Community and Preventive Medicine, Isfahan Medical Sciences University, Isfahan, Iran
  3. 3. Isfahan Medical Sciences University, Isfahan, Iran

Source: International Journal of Cancer Research Published:2007


Abstract

To evaluate the influence of family history on the survival of breast cancer in Iranian women, the following study was designed. During 10 years from 1997-2007, 663 women with invasive breast cancer were selected from a private oncology clinic in Isfahan, prospectively. Both demographic variables and tumor characteristics was collected. Analysis was conducted by Cox regression model. A positive family history was found in 125 (19%) patients. Survival rate did not vary between subjects with positive and negative family history of breast cancer in both disease free and overall survival. Cox regression analysis after adjustment for other prognostic factors was determined that family history did not impact on the mortality rate of breast cancer. But lymph node involvement increased the relapse of tumor twice, approximately (RR = 1.9 95% CI = 1.35-2.77). Present findings did not demonstrate any association between breast cancer family history and the prognosis of cancer in Iranian women. It is important that is perceived the family history is a major risk factor for breast cancer but it does not effect on the survival and mortality rate of breast cancer. © 2007 Academic Journals Inc.
Related Docs
View other Related Docs
1. Survival Analysis of Iranian Patients With Breast Cancer Using Joint Frailty Model With a Cure Rate, Middle East Journal of Cancer (2021)
2. Clinicopathological Analysis of Patients With Breast Cancer and Their Families, Iranian Journal of Blood and Cancer (2016)
3. Risk Factors of Developing a Second Malignancy Following Treatment of a First Primary Breast Cancer, Iranian Journal of Cancer Prevention (2013)
4. Relations of Disease-Free Survival and Overall Survival With Age and Primary Metastases in Patients With Breast Cancer, Journal of Isfahan Medical School (2013)
5. Adjustment Process in Iranian Men to Their Wives' Breast Cancer, European Journal of Cancer Care (2016)
6. Fatalism in Breast Cancer and Performing Mammography on Women With or Without a Family History of Breast Cancer, BMC women's health (2019)
7. Determinants of Prognosis in Triple-Negative Breast Cancer: Report From a Large Breast Cancer Registry, Archives of Iranian Medicine (2021)
8. Investigation the Quality of Life and Its Relation With Clinical and Demographic Characteristics in Women With Breast Cancer Under Chemotherapy, International Journal of Preventive Medicine (2012)
Experts (# of related papers)
View all Related Experts
Ziba Farajzadegan (3)
Mitra Savabi (3)
Other Related Docs
9. Cancer Epidemiology and Trends in Sistan and Baluchestan Province, Iran, Medical Journal of the Islamic Republic of Iran (2015)
10. Association Between Healthy Lifestyle Score and Breast Cancer, Nutrition Journal (2020)
11. Rational, Design and Preliminary Results of a Cohort Study on Breast and Colorectal Cancer to Develop a Risk Assessment Model to Predict Future Cardiovascular Events. “Cardio Vascular Events in Breast and Colorectal Cancers (Cibc) Study”, Current Problems in Cardiology (2022)
12. Trends in Breast Cancer Incidence Rates by Age and Tumor Characteristics of Women in the City of Isfahan for the Period 2001-2010: An Application of Joinpoint Analysis, Journal of Research in Medical Sciences (2014)
13. Relationship Between Breast Cancer and Dietary Inflammatory Index; a Case–Control Study, Clinical Nutrition ESPEN (2022)
14. National Surveillance of Cancer Survival in Iran (Irancansurv): Analysis of Data of 15 Cancer Sites From Nine Population-Based Cancer Registries, International Journal of Cancer (2022)
15. Breast Cancer Risk Assessment Using Gail Model in 35 to 69-Year-Old Women Referred to the Breast Cancer Screening Center at Omid Hospital in Isfahan, Iran, From 2008 to 2016, Journal of Kerman University of Medical Sciences (2020)
16. The Transtheoretical Model, Health Belief Model, and Breast Cancer Screening Among Iranian Women With a Family History of Breast Cancer, Journal of Research in Medical Sciences (2016)
17. Locoregional Recurrence of Breast Cancer and Its Predictive Factors, Journal of Isfahan Medical School (2012)
18. A Scoping Review of 20 Years Breast Cancer Screening Programs in Iran, Iranian Journal of Public Health (2025)
19. Cancer in Iran 2008 to 2025: Recent Incidence Trends and Short-Term Predictions of the Future Burden, International Journal of Cancer (2021)
20. Hardiness and Optimism in Women With Breast Cancer, Iranian Journal of Nursing and Midwifery Research (2018)
21. The Performance of the Nottingham Prognosis Index and the Adjuvant Online Decision Making Tool for Prognosis in Early-Stage Breast Cancer Patients, International Journal of Preventive Medicine (2015)
22. Multiple Associations of Clinicopathological Characteristics and Risk Factors of Colorectal Cancer in the Iranian Population, Middle East Journal of Cancer (2021)
23. Bivariate Spatiotemporal Disease Mapping of Cancer of the Breast and Cervix Uteri Among Iranian Women, Geospatial Health (2018)
24. Clinical Breast Cancer Registry of Ir. Iran (Cbcr-Ir): Study Protocol and First Results, Archives of Iranian Medicine (2023)
25. Living Under a Cloud of Threat: The Experience of Iranian Female Caregivers With a First-Degree Relative With Breast Cancer, Psycho-Oncology (2017)
26. Epidemiology and Trend of Cancers in the Province of Kerman: Southeast of Iran, Asian Pacific Journal of Cancer Prevention (2015)
27. Iranian Women Diagnosed With Breast Cancer a Decade Earlier Than British Women?, Journal of Kerman University of Medical Sciences (2022)
28. Genomic Rearrangement Screening of the Brca1 From Seventy Iranian High-Risk Breast Cancer Families, Journal of Research in Medical Sciences (2016)
29. Awareness Levels About Breast Cancer Risk Factors, Early Warning Signs, and Screening and Therapeutic Approaches Among Iranian Adult Women: A Large Population Based Study Using Latent Class Analysis, BioMed Research International (2014)
30. Relationship Between Breastfeeding Factors and Breast Cancer in Women Referred to Seyed Al-Shohada Hospital in Isfahan, Iran, Iranian Journal of Nursing and Midwifery Research (2016)
31. Health Education Models Application by Peer Group for Improving Breast Cancer Screening Among Iranian Women With a Family History of Breast Cancer: A Randomized Control Trial, Medical Journal of the Islamic Republic of Iran (2018)
32. Evaluation of Risk Factors in Developing Breast Cancer With Expectation Maximization Algorithm in Data Mining Techniques, Journal of Medical Imaging and Health Informatics (2016)
33. Risk Factors of Metastasis in Women With Breast Cancer in Isfahan, Iran, Journal of Isfahan Medical School (2012)
34. Identification of Effective Factors in Breast Cancer Survival in Isfahan Using Machine Learning Techniques, Journal of Advances in Medical and Biomedical Research (2024)
35. Transition to the New Role of Caregiving for Families of Patients With Breast Cancer: A Qualitative Descriptive Exploratory Study, Supportive Care in Cancer (2016)
36. Predicting Place of Death of Patients With Advanced Cancer Receiving Home-Based Palliative Care Services in Iran, BMC Palliative Care (2024)
37. Environmental Risk Factors Associated With Sporadic Colorectal Cancer in Isfahan, Iran, Middle East Journal of Cancer (2018)
38. Hereditary Nonpolyposis Colorectal Cancer and Familial Colorectal Cancer in Central Part of Iran, Isfahan, Journal of Research in Medical Sciences (2012)
39. Investigating the Frequency Distribution of Breast Imaging Reporting and Data System (Birads) Classification and Its Changes in Mammographic Findings in a Private Center in Isfahan City, Iran, During the Years 2010 to 2014, Journal of Isfahan Medical School (2018)
40. Investigation of Prognostic Factors in Breast Cancer and Their Relationship With Age and Cancer Stage, Journal of Isfahan Medical School (2012)
41. Iranian Version of the Quality of Life in Adult Cancer Survivors (Qlacs) Questionnaire: Examining Face and Content Validity, Exploratory Factor Analysis and Reliability, Shiraz E Medical Journal (2021)
42. The Most Common Cancers in Iranian Women, Iranian Journal of Public Health (2009)
43. A Study of the Long-Term Trend of Epidemiological and Clinical Indices of Breast Cancer in Isfahan, Journal of Isfahan Medical School (2012)
44. Comparison of Bayesian Spatial Ecological Regression Models for Investigating the Incidence of Breast Cancer in Iran, 2005-2008, Asian Pacific Journal of Cancer Prevention (2015)
45. Cancer Incidence and Prevalence in Isfahan: Application of Mortality Data to Estimates and Projects for the Period 2001-2015, International Journal of Preventive Medicine (2012)
46. Burden of Breast Cancer and Attributable Risk Factors in the North Africa and Middle East Region, 1990–2019: A Systematic Analysis for the Global Burden of Disease Study 2019, Frontiers in Oncology (2023)
47. Knowledge of and Attitudes Toward Breast Self-Examination in Iranian Women: A Multi-Center Study, Asian Pacific Journal of Cancer Prevention (2011)
48. Detection of Prognostic Factors in Metastatic Breast Cancer, Journal of Research in Medical Sciences (2013)
49. Challenges Related to Health Care for Iranian Women With Breast Cancer During the Covid-19 Pandemic: A Qualitative Study, Asian Journal of Social Health and Behavior (2023)
50. Determinants of Mammography Screening Behavior in Iranian Women: A Population-Based Study, Journal of Research in Medical Sciences (2012)