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Mitral Valve Repair of the Anterior Leaflet: Are We There Yet? Publisher Pubmed



Bahiraie P1 ; Soleimani H2, 3, 4 ; Heydari N5 ; Najafi K6 ; Karlas A7, 8, 9, 10 ; Avgerinos DV11 ; Samanidis G11 ; Kuno T12 ; Doulamis IP13 ; Ioannis I11 ; Spilias N14 ; Hosseini K2, 3 ; Kampaktsis PN15
Authors
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Authors Affiliations
  1. 1. School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  2. 2. Cardiac Primary Prevention Research Center, Cardiovascular Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Tehran Heart Center, Cardiovascular Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Faculty of medicine, Isfahan University of medical science, Isfahan, Iran
  6. 6. Faculty of medicine, Tehran University of medical sciences, Tehran, Iran
  7. 7. Institute for Biological and Medical Imaging, Helmholtz Zentrum Munchen, Neuherberg, Germany
  8. 8. Department for Vascular and Endovascular Surgery, Klinikum rechts der Isar, Technical University of Munich (TUM), Munich, Germany
  9. 9. Chair of Biological Imaging at the Central Institute for Translational Cancer Research (TranslaTUM), School of Medicine, Technical University of Munich, Munich, Germany
  10. 10. DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany
  11. 11. Onassis Cardiac Surgery Center, Athens, Greece
  12. 12. Division of Cardiology, Montefiore Medical Center, NYC, NY, United States
  13. 13. Department of Surgery, The Johns Hopkins Hospital and School of Medicine, Baltimore, MD, United States
  14. 14. Division of Cardiovascular Medicine, University of Miami Health System, Miami, FL, United States
  15. 15. Division of Cardiology, Columbia University Irving Medical Center, NYC, NY, United States

Source: Hellenic Journal of Cardiology Published:2024


Abstract

Mitral regurgitation is one of the most prevalent valvulopathies with a disease burden that incurs significant healthcare costs globally. Surgical repair of the posterior mitral valve leaflet is a standard treatment, but approaches for repairing the anterior mitral valve leaflet are not widely established. Since anterior leaflet involvement is less common and more difficult to repair, fewer studies have investigated its natural history and treatment options. In this review, we discuss surgical techniques for repairing the anterior leaflet and their outcomes, including survival, reoperation, and recurrence of regurgitation. We show that most patients with mitral regurgitation from the anterior leaflet can be repaired with good outcomes if performed at centers with expertise. Additionally, equal consideration for early repair should be given to patients with mitral regurgitation from both anterior and posterior pathology. However, more studies to better evaluate the efficacy and safety of anterior mitral valve leaflet repair are needed. © 2024 Hellenic Society of Cardiology