Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Dengue Virus: Etiology, Epidemiology, Pathobiology, and Developments in Diagnosis and Control – a Comprehensive Review Publisher Pubmed



Pourzangiabadi M1 ; Najafi H2 ; Fallah A3 ; Goudarzi A4 ; Pouladi I2
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Microbiology, Faculty of Science, Kerman Branch, Islamic Azad University, Kerman, Iran
  2. 2. Department of Microbiology and Immunology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
  3. 3. Department of Bacteriology and Virology, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  4. 4. Department of Clinical Science, Faculty of Veterinary Medicine, Science and Research Branch, Islamic Azad University, Tehran, Iran

Source: Infection, Genetics and Evolution Published:2025


Abstract

Dengue flavivirus (DENV) is the virus that causes dengue, one of the most dangerous and common viral diseases in humans that are carried by mosquitoes and can lead to fatalities. Every year, there are over 400 million cases of dengue fever worldwide, and 22,000 fatalities. It has been documented in tropical and subtropical climates in over 100 nations. Unfortunately, there is no specific treatment approach, but prevention, adequate awareness, diagnosis in the early stages of viral infection and proper medical care can reduce the mortality rate. The first licensed vaccine for dengue virus (CYD Denvaxia) was quadrivalent, but it is not approved in all countries. The primary barriers to vaccine development include inadequate animal models, inadequate etiology mechanistic studies, and adverse drug events. This study provides current knowledge and a comprehensive view of the biology, production and reproduction, transmission, pathogenesis and diagnosis, epidemiology and control measures of dengue virus. © 2024
Related Docs
1. Modulating Neurological Complications of Emerging Infectious Diseases: Mechanistic Approaches to Candidate Phytochemicals, Frontiers in Pharmacology (2021)
2. Detection of West Nile Virus Genome and Specific Antibodies in Iranian Encephalitis Patients, Epidemiology and Infection (2012)
Experts (# of related papers)
Behrooz Ataei (1)