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Tonic Pupil, a Paraneoplastic Neuro-Ophtalmological Disease Associated With Occult Breast Cancer Publisher Pubmed



Peyman A1 ; Kabiri M2 ; Peyman M3
Authors
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Authors Affiliations
  1. 1. Department of Ophthalmology, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Department of Ophthalmology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  3. 3. Department of Ophthalmology, Faculty of Medicine Building, University of Malaya, Kuala Lumpur, Malaysia

Source: Breast Journal Published:2015


Abstract

Here, we present a case of tonic pupil associated with occult breast cancer as a paraneoplastic neuro-ophthalmology syndrome. A 45-year-old woman developed progressive photophobia and blurred vision due to unilateral Adie's tonic pupil. Magnetic resonance image of her brain and neurological examination (including deep tendon reflexes) were normal at first visit. Follow-up examinations performed by ophthalmologist every 6 month without any change in her condition. After 2 years, patient discovered a mass in her breast which identified to be malignant after diagnostic procedures. Despite surgical and medical treatment for cancer, no change in the ocular condition was happened. © 2015 Wiley Periodicals, Inc.