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Macrocyclic Diterpenoids From the Iranian Plant Euphorbia Bungei Boiss. Publisher Pubmed



Shokoohinia Y1 ; Chianese G2 ; Zolfaghari B1 ; Sajjadi SE1 ; Appendino G3 ; Taglialatelascafati O2
Authors
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Authors Affiliations
  1. 1. Department of Pharmacognosy, School of Pharmacy, Isfahan University of Medical Sciences, 81745 Isfahan, Hezar Jarib Ave., Iran
  2. 2. Dipartimento di Chimica Delle Sostanze Naturali, Universita di Napoli Federico II, I-80131 Napoli, Via D. Montesano 49, Italy
  3. 3. Dipartimento di Scienze Chimiche Alimentari, Farmaceutiche e Farmacologiche, Universita Del Piemonte Orientale, 28100 Novara, Via Bovio 6, Italy

Source: Fitoterapia Published:2011


Abstract

An acetone extract from the aerial parts of Euphorbia bungei afforded three new (2, 3 and 5) and one known (4) macrocyclic diterpenoids. Several cycloartane triterpenoids were also obtained, two of which (6a and 6b) were assayed for antiviral effects. The structures of all new compounds were elucidated using modern spectroscopic methods including 2D NMR and HRMS. © 2010 Elsevier B.V. All rights reserved.
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