Bone Densitometry and Fat Index After Sleeve and Subsleeve Gastrectomy in Animal Model Publisher

Summary: Study finds no significant weight loss or bone density difference after obesity surgeries in rabbits. Surprising results on subsleeve vs. sleeve gastrectomy! What now for obesity surgery? #BariatricSurgery #Research

Khazraei H ; Hosseini SV ; Amini M ; Amirzadeh S ; Dehghanian A ; Sobhani Z ; Kasraei H
Source: Advanced Biomedical Research Published:2022

Abstract

Background: Previous studies have reported that gastrectomy and fundectomy can induce osteopenia. Body fat index is a new index of obesity that shows central obesity and other risks of obesity. Sleeve gastrectomy (SG) is a bariatric surgery and a new technique introduced as subsleeve, which only resected fundus of the stomach. In this study, it has been shown the effect of subsleeve and SG on fat index and bone densitometry in an animal model. Materials and Methods: Rabbits were underlined SG, fundectomy (surgical removal of fundus), or sham-operated (controls without any resection), and after 12 weeks, fat index and bone densitometry were obtained. Results: Our study showed that there was no significant difference between SG and fundectomy groups in bone mass density and fat mass after surgery in comparison with presurgery condition. SG group were associated with lower fat index and bone density, and it showed significantly decrease in weight after 1.5 months. Conclusion: Sub-SG did not show any significant effect on fat index and bone densitometry in comparison with SG. However, we found lower fat index in sleeve group of rabbits, but it was not statistically significant. © 2022 Elsevier B.V., All rights reserved.