Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Eco-Friendly and Sustainable Synthesis of Biocompatible Nanomaterials for Diagnostic Imaging: Current Challenges and Future Perspectives Publisher



Jamalipour Soufi G1 ; Iravani S2
Authors
Show Affiliations
Authors Affiliations
  1. 1. Radiology Department, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Faculty of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Green Chemistry Published:2020


Abstract

Conventional organic dyes and inorganic fluorescent contrast agents have been obstructed in bioimaging and biomedical applications, because of their intrinsic drawbacks including toxicity and poor biocompatibility. Thus, there is a pressing need to develop innovative classes of nanomaterials and fluorescent contrast agents with merits of high photostability, remarkable safety, and significant biocompatibility for biomedical and clinical applications. In this critical review, recent trends and future prospects regarding the eco-friendly and sustainable synthesis of biocompatible nanomaterials for diagnosis/imaging, bioimaging and cellular imaging are discussed as well as important challenges for sophisticated sensitive and noninvasive clinical diagnostic imaging. Particularly, the potential of biocompatible nanocontrast agents is discussed for further improvements of magnetic resonance imaging (MRI) and computed tomography (CT) scanning performance, remarkably for cancer diagnosis/imaging and therapy. However, it appears that further investigations and comprehensive evaluations should be accomplished to find innovative strategies and relevant challenges in this important field of science. © 2020 The Royal Society of Chemistry.
Related Docs
View other Related Docs
1. Nanoscale Contrast Agents for Magnetic Resonance Imaging: A Review, ACS Applied Nano Materials (2022)
2. Medical Imaging Modalities Using Nanoprobes for Cancer Diagnosis: A Literature Review on Recent Findings, Journal of Research in Medical Sciences (2019)
3. Recent Nanotheranostics Applications for Cancer Therapy and Diagnosis: A Review, IET Nanobiotechnology (2021)
4. Greener Synthesis of Lignin Nanoparticles and Their Applications, Green Chemistry (2020)
5. Imaging and Therapeutic Capabilities of the Aunps@Mnco3/Mn3o4, Coated With Paa and Integrated With Folic Acid, Doxorubicin and Propidium Iodide for Murine Breast Cancer, Journal of Drug Delivery Science and Technology (2022)
6. A Literature Review on Multimodality Molecular Imaging Nanoprobes for Cancer Detection, Polish Journal of Medical Physics and Engineering (2019)
7. Chitosan–Imidazolium Core–Shell Nanoparticles of Gd-Mn-Mo Polyoxometalate As Novel Potential Mri Nano-Agent for Breast Cancer Detection, Micromachines (2023)
8. Therapeutic Effect of Deferrioxamine Conjugated to Pegylated Gold Nanoparticles and Complexed With Mn(Ii) Beside the Ct Scan and Mri Diagnostic Studies, Colloids and Surfaces A: Physicochemical and Engineering Aspects (2019)
Experts (# of related papers)
View all Related Experts
Daryoush Shahbazi-Gahrouei (27)
Seyed Hossein Hejazi (5)
Other Related Docs
9. Green Sonochemical Synthesis Platinum Nanoparticles As a Novel Contrast Agent for Computed Tomography, Materials Today Communications (2021)
10. Porphyrin–Iron Oxide Nanoparticle Functionalized With Trastuzumab (Ion–Pp–Tz) Potential Mr Imaging Probe for Breast Cancer Cells, Applied Physics A: Materials Science and Processing (2022)
11. Theranostic Applications of Metal–Organic Frameworks (Mofs)-Based Materials in Brain Disorders: Recent Advances and Challenges, Inorganic Chemistry Communications (2021)
12. Challenges and Opportunities of Using Fluorescent Metal Nanocluster-Based Colorimetric Assays in Medicine, ACS Omega (2023)
13. Mxenes in Photomedicine: Advances and Prospects, Chemical Communications (2022)
14. Bio-Based Synthesis of Magnetic Nanoparticles and Their Applications, Nanotechnology in the Life Sciences (2019)
15. Facile, Rapid and Efficient Isolation of Circulating Tumor Cells Using Aptamer-Targeted Magnetic Nanoparticles Integrated With a Microfluidic Device, RSC Advances (2022)
16. Technetium-99M Chelator-Free Radiolabeling of Specific Glutamine Tumor Imaging Nanoprobe: In Vitro and in Vivo Evaluations, International Journal of Nanomedicine (2018)
17. Hollow Mesoporous Prussian Blue Nanoparticles for in Vivo Synergistic Chemo-Photothermal Cancer Therapy and Dual-Mode Magnetic Resonance/Fluorescence Imaging, ACS Applied Nano Materials (2024)
18. Mxenes for Cancer Therapy and Diagnosis: Recent Advances and Current Challenges, ACS Biomaterials Science and Engineering (2021)
19. Mxenes and Mxene-Based Materials With Cancer Diagnostic Applications: Challenges and Opportunities, Comments on Inorganic Chemistry (2022)
20. Biowaste-Derived Carbon Dots: A Perspective on Biomedical Potentials, Molecules (2022)
21. Superparamagnetic Iron Oxide-C595: Potential Mr Imaging Contrast Agents for Ovarian Cancer Detection, Journal of Medical Physics (2013)
22. Folate-Graphene Chelate Manganese Nanoparticles As a Theranostic System for Colon Cancer Mr Imaging and Drug Delivery: In-Vivo Examinations, Journal of Drug Delivery Science and Technology (2019)
23. Breast Cancer Cell Targeted Mr Molecular Imaging Probe: Anti-Muc1 Antibody-Based Magnetic Nanoparticles, Journal of Physics: Conference Series (2017)
24. Mn(Ii) & Gd(Iii) Deferrioxamine Complex Contrast Agents & Temozolomide Cancer Prodrug Immobilized on Folic Acid Targeted Graphene/Polyacrylic Acid Nanocarrier: Mri Efficiency, Drug Stability & Interactions With Cancer Cells, Colloids and Surfaces A: Physicochemical and Engineering Aspects (2022)
25. Plants and Plant-Based Polymers As Scaffolds for Tissue Engineering, Green Chemistry (2019)
26. Novel Mr Imaging Nanoprobe for Hepatocellular Carcinoma Detection Based on Manganese–Zinc Ferrite Nanoparticles: In Vitro and in Vivo Assessments, Journal of Cancer Research and Clinical Oncology (2023)
27. Hierarchical Multifunctional Graphene Oxide Cancer Nanotheranostics Agent for Synchronous Switchable Fluorescence Imaging and Chemical Therapy, Microchimica Acta (2020)
28. Synthesis and Characterisation of Iron Oxide Nanoparticles Conjugated With Epidermal Growth Factor Receptor (Egfr) Monoclonal Antibody As Mri Contrast Agent for Cancer Detection, IET Nanobiotechnology (2019)
29. A Review on Application of Novel Solid Nanostructures in Drug Delivery, Journal of Nano Research (2018)
30. Recent Advances in Nanomaterials Development for Nanomedicine and Cancer, ACS Applied Bio Materials (2021)
31. A Drug Delivery System Based on Nanocomposites Constructed From Metal-Organic Frameworks and Mn3o4 Nanoparticles: Preparation and Physicochemical Characterization for Bt-474 and Mcf-7 Cancer Cells, Colloids and Surfaces B: Biointerfaces (2021)
32. Biopolymer Nanovehicles for Oral Delivery of Natural Anticancer Agents, Advanced Functional Materials (2023)
33. Trastuzumab Conjugated Porphyrin-Superparamagnetic Iron Oxide Nanoparticle: A Potential Ptt-Mri Bimodal Agent for Herceptin Positive Breast Cancer, Photodiagnosis and Photodynamic Therapy (2020)
34. Functionalized Magnetic Nanoparticles for Cancer Therapy, Functionalized Nanomaterials for Cancer Research: Applications in Treatments, Tools and Devices (2024)
35. Folic Acid-Functionalized Gadolinium-Loaded Phase Transition Nanodroplets for Dual-Modal Ultrasound/Magnetic Resonance Imaging of Hepatocellular Carcinoma, Talanta (2021)
36. Cobalt Zinc Ferrite Nanoparticles As a Potential Magnetic Resonance Imaging Agent: An in Vitro Study, Avicenna Journal of Medical Biotechnology (2015)
37. Gadolinium-Hematoporphyrin: New Potential Mri Contrast Agent for Detection of Breast Cancer Cell Line (Mcf-7), Journal of Research in Medical Sciences (2005)
38. Magnetic Iron Oxide Nanoparticles As T2 Mr Imaging Contrast Agent for Detection of Breast Cancer (Mcf-7) Cell, Avicenna Journal of Medical Biotechnology (2017)
39. Smart Mxene Quantum Dot-Based Nanosystems for Biomedical Applications, Nanomaterials (2022)
40. Anti-Cd24 Bio Modified Pegylated Gold Nanoparticles As Targeted Computed Tomography Contrast Agent, Advanced Pharmaceutical Bulletin (2018)
41. Bevacizumab and Folic Acid Dual-Targeted Gadolinium-Carbon Dots for Fluorescence/Magnetic Resonance Imaging of Hepatocellular Carcinoma, Journal of Drug Delivery Science and Technology (2021)
42. Synthesis and Application of Fe3o4@Au Composite Nanoparticles As Magnetic Resonance/Computed Tomography Dual-Modality Contrast Agent, Journal of Medical Signals and Sensors (2020)
43. Fabrication of a Biocompatible & Biodegradable Targeted Theranostic Nanocomposite With Ph-Controlled Drug Release Ability, Journal of Drug Delivery Science and Technology (2022)
44. Aptamer-Conjugated Magnetic Nanoparticles As Targeted Magnetic Resonance Imaging Contrast Agent for Breast Cancer, Journal of Medical Signals and Sensors (2016)
45. A Review of Imaging Methods and Recent Nanoparticles for Breast Cancer Diagnosis, Information (Switzerland) (2024)
46. Plant Molecular Farming: Production of Metallic Nanoparticles and Therapeutic Proteins Using Green Factories, Green Chemistry (2019)
47. Recent Metal Nanotheranostics for Cancer Diagnosis and Therapy: A Review, Diagnostics (2023)
48. Assessment of Ploy Dopamine Coated Fe3o4 Nanoparticles for Melanoma (B16-F10 and A-375) Cells Detection, Anti-Cancer Agents in Medicinal Chemistry (2020)
49. Novel Nanosized Gd3+-Algd-G2 -C595: In Vivo Dual Selective Muc-1 Positive Tumor Molecular Mr Imaging and Therapeutic Agent, Journal of Nanomedicine and Nanotechnology (2012)
50. Mxenes in Cancer Nanotheranostics, Nanomaterials (2022)