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Effect of Corticosteroid Therapy in Esophageal Stricture of a Child With Chronic Granulomatous Disease Pubmed



Alborzi A1, 3 ; Mostafavi N2 ; Pouladfar GR1
Authors
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Authors Affiliations
  1. 1. Professor Alborzi Clinical Microbiology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
  2. 2. Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Professor Alborzi Clinical Microbiology Research Center, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran

Source: Iranian Journal of Allergy, Asthma and Immunology Published:2008


Abstract

In chronic granulomatous disease (CGD) patients, esophageal stricture is a rare complication and the treatment of choice is still controversial. There are few reports of successful therapy with antibiotics, corticosteroids, multiple balloon dilatations or their combination. We report a 3-three-year-old Iranian boy with recurrent esophageal obstruction due to CGD. The patient transiently responded to dilatation in one occasion and at another time to short term steroid therapy. We observed an excellent response when long term and high dose of corticosteroid was administered. It showed that a long term and high dose steroid therapy is more effective than a short term in a patient with CGD and esophageal stricture. Copyright© 2008, All rights reserved.