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Antifungal Activity of Myrtus Communis L. Esssential Oil Against Clinical Isolates of Aspergillus



Mohammadi R1 ; Esfahani SHM2 ; Shadzi S3 ; Moattar F4
Authors
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Authors Affiliations
  1. 1. Tarbiat Modarres University, Tehran, Iran
  2. 2. Tehran University of Medical Sciences, Tehran, Iran
  3. 3. School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  4. 4. School of Pharmacy, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Journal of Isfahan Medical School Published:2008

Abstract

Background: Aspergillusis is an opportunistic fungal disease caused by different species of Aspergillus. Clinical manifestation and severity of disease related to physiological conditions of host body, involved organs and Aspergillus species. Myrtle is dried leaves of Myrtus communis L. has medicinal properties. A leaf of this plant has 1.5-2% essential oil and has antimicrobial effect. Method: In this study, broth microdilution method was used. Essential oil of plant was extracted by means of Clevenger apparatus and used on isolates; then account of turbidity caused in wells, their MIC was calculated. Finding: Number of samples was twenty six. Five isolates did not grow up to the dilution of 1/8th (MIC=1/4th), eight isolates up to 1/16th (MIC = 1/8th), ten isolates up to 1/32nd (MIC=1/16th) and three isolates up to 1/64th (MIC=1/32nd) of essential oil. Conclusion: In view of the fact that Myrtus communis essential oil was effective against all isolates in this research we recommend the investigation of its antifungal properties Invivo and the effect of pH and temperature on its antimicrobial properties. © 2008, Isfahan University of Medical Sciences(IUMS). All rights reserved.
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