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Parasites and Cancers: Parasite Antigens As Possible Targets for Cancer Immunotherapy Publisher Pubmed



Darani HY1 ; Yousefi M2
Authors
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Authors Affiliations
  1. 1. Department of Parasitology and Mycology, Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Student Research Committee, Shahrekord University of Medical Sciences, Shahrekord, Iran

Source: Future Oncology Published:2012


Abstract

An adverse relationship between some parasite infections and cancer in the human population has been reported by different research groups. Anticancer activity of some parasites such as Trypanosoma cruzi, Toxoplasma gondii, Toxocara canis, Acantamoeba castellani and Plasmodium yoelii has been shown in experimental animals. Moreover, it has been shown that cancer-associated mucin-type O-glycan compositions are made by parasites, therefore cancers and parasites have common antigens. In this report anticancer activities of some parasites have been reviewed and the possible mechanisms of these actions have also been discussed. © 2012 Future Medicine Ltd.
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