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Composite Lymphoma in a Patient With Ulcerative Colitis: A Case Report



Ashrafi F1 ; Kowsari F2 ; Darakhshandeh A3 ; Adibi P4
Authors
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Authors Affiliations
  1. 1. Hematology and Oncology section, Department of Internal Medicine, School of Medicine, Isfahan University of Medical sciences, Isfahan, Iran
  2. 2. Department of Pathology, School of Medicine, Tehran University of Medical sciences, Tehran, Iran
  3. 3. Department of Internal Medicine, School of Medicine, Isfahan University of Medical sciences, Isfahan, Iran
  4. 4. Gastroenterology section, Department of Internal Medicine, School of Medicine, Isfahan University of Medical sciences, Isfahan, Iran

Source: International Journal of Hematology-Oncology and Stem Cell Research Published:2014

Abstract

A 45-year-old female patient with a diagnosis of ulcerative colitis complicated with composite lymphoma in the spleen and para-aortic lymph node presented with a one-month history of malaise, weakness and fatigue. Only mesalamine kept ulcerative colitis under control. In physical examination, splenomegaly was revealed and pancytopenia was obtained from laboratory data. Computed tomography scan revealed para-aortic mediastinal lymphadenopathy with splenomegaly. Splenectomy and excisional biopsy of abdominal lymph node were performed and disease was diagnosed as composite lymphoma, consisting of diffuse large B-cell lymphoma and nodular sclerosing Hodgkin lymphoma. © 2014, Tehran University of Medical Sciences (TUMS). All rights reserved.
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