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Syringotropic Lichen Planus: An Unusual Presentation of a Common Dermatosis - a Report of 2 Cases Publisher



Mohaghegh F1 ; Khodashenas Z2 ; Saber M1 ; Sohrabi H3
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Authors Affiliations
  1. 1. Department of Dermatology, Skin Diseases, and Leishmaniasis Research Center, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Department of Dermatology, Faculty of Medicine, Shahed University, Tehran, Iran
  3. 3. School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Case Reports in Dermatology Published:2024


Abstract

Introduction: Lichen planus (LP) is a chronic inflammatory dermatosis that causes plaques and itchy papules on the skin, as well as erosion and ulcers in the mucous membranes. LP is characterized by a dense dermal T-cell infiltration. Perieccrine inflammation can be seen in a variety of dermatoses, but genuine lymphocyte permeation of the secretory coil or lymphocytic syringotropism is a rare sign that is typically seen in mycosis fungoides. Case Presentation: In this study, we present 2 uncommon instances of lymphocytic syringotropism in LP. Histopathological examination revealed dense T-cell infiltration and lymphocytic involvement of eccrine glands, confirming syringotropism. Conclusion: Lymphocytic syringotropism is an uncommon finding in LP. Its presence broadens the histopathological spectrum of LP and highlights the need to differentiate it from lymphoproliferative disorders like mycosis fungoides. © 2024 The Author(s). Published by S. Karger AG, Basel.
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