Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Hypothyroidism Is Prevalent Among Adult Women With Chronic Lower Urinary Tract Symptoms Publisher Pubmed



Zargham M1 ; Hajian MR2 ; Alizadeh F1 ; Eslami MJ1 ; Khalili Boroujeni N3 ; Gholipour F4
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Urology, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Urology and Nephrology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  3. 3. Isfahan Endocrine and Metabolism Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  4. 4. Isfahan Kidney Disease Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

Source: LUTS: Lower Urinary Tract Symptoms Published:2022


Abstract

Objective: To define the prevalence of hypothyroidism in women with chronic lower urinary tract symptoms (LUTS) and to compare the severity of each symptom between patients with hypothyroidism and controls. Subjects and methods: In this prospective observational study, we screened all adult women who came to the urology clinic between March 2017 and September 2020, and enrolled patients with chronic LUTS in the study. We assessed thyroid function. We evaluated the severity of voiding and storage urinary symptoms by the International Prostate Symptom Score. We also assessed the severity of urge urinary incontinence (UUI) and stress urinary incontinence (SUI). For between-group analysis, we selected age-matched cases and controls and compared them regarding the distribution and severity of urinary symptoms. Results: Seven hundred and twenty-five women with a mean age of 51.7 ± 14.0 years were included in the final analysis. Two hundred fifty-eight patients (35.6%) had hypothyroidism. Age-matched case and control groups consisting of 210 patients each were selected. There was no significant difference in the severity and distribution of voiding LUTS and UUI between the study groups (P values >0.05). The severity of storage symptoms was lower in patients with hypothyroidism (P = 0.04). Sixty-seven patients with hypothyroidism (31.9%) had SUI, which was significantly higher than controls (23.3%) (P = 0.03). Conclusion: More than one-third of women with chronic LUTS have hypothyroidism which is much more frequent than in the general population. We also suggest a possible relationship between hypothyroidism and the severity of SUI and an inverse relationship between hypothyroidism and storage symptoms. © 2022 John Wiley & Sons Australia, Ltd.
Related Docs
View other Related Docs
1. Urodynamic Characteristics of Chronic Lower Urinary Tract Symptoms in Women With Hypothyroidism, Journal of Isfahan Medical School (2015)
2. Incidence of Thyroid Dysfunction in an Iranian Adult Population: The Predictor Role of Thyroid Autoantibodies: Results From a Prospective Population-Based Cohort Study, European Journal of Medical Research (2017)
3. The Sexual Dysfunction in Women With Thyroid Disorders: A Meta-Analysis, BMC Endocrine Disorders (2024)
4. Bladder Involvement in Thyroid Dysfunction, Journal of Research in Medical Sciences (2013)
5. Population-Based Survey of Urinary Incontinence, Overactive Bladder, and Other Lower Urinary Tract Symptoms in Five Developing Countries: Results of the Bebic Study, Neurourology and Urodynamics (2025)
6. The Prevalence of Lower Urinary Tract Symptoms (Luts) and Incontinence in Iranian Women, Urology Journal (2020)
7. Translation and Linguistic Validation of the Persian Version of the Bristol Female Lower Urinary Tract Symptoms Instrument, International Urogynecology Journal (2017)
8. The Prevalence of Thyroid Dysfunction in an Iodine-Sufficient Area in Iran, Archives of Iranian Medicine (2009)
Experts (# of related papers)
View all Related Experts
Mahtab Zargham (9)
Farshid Alizadeh (3)
Other Related Docs
9. Association Between Lower Urinary Tract Symptoms (Luts) and Obsessive-Compulsive Disorders (Ocd) in Women: A Study Based on Urodynamic Findings and Micturition Problem, Neurourology and Urodynamics (2022)
10. Reliability and Validity of the Persian Language Version of the Female Lower Urinary Tract Symptoms' Long Form Questionnaire, Iranian Journal of Nursing and Midwifery Research (2018)
11. Does Significant Weight Loss After Bariatric Surgery Affect Sexual Function and Urinary Symptoms? an Iranian Study, Obesity Surgery (2023)
12. The Prevalence of Lower Urinary Tract Symptoms Among Employee and Student Women in Isfahan University of Medical Sciences, Isfahan, Iran, Journal of Isfahan Medical School (2018)
13. The Effect of Two Types of Exercise Therapy on Improvement of Stress Urinary Incontinence in Women, Journal of Isfahan Medical School (2016)
14. How Much Is There a Correlation Between Clinical Symptoms and Urodynamic Findings of Overactive Bladder Patients?, Journal of Obstetrics, Gynecology and Cancer Research (2025)
15. Comparison of Severity of Osteoporosis in Women With Primary Hypothyroidism and Healthy Women, Journal of Isfahan Medical School (2012)
16. Meta-Analytical and Meta-Regression Evaluation of Subclinical Hyperthyroidism's Effect on Male Reproductive Health: Hormonal and Seminal Perspectives, Reproductive Sciences (2024)
17. Reliability and Validity of the Persian Language Version of the International Consultation on Incontinence Questionnaire - Male Lower Urinary Tract Symptoms (Iciq-Mluts), LUTS: Lower Urinary Tract Symptoms (2018)
18. Reliability and Validity of the Quality of Life Questionnaire in Iranian Patients With Lower Urinary Tract Symptoms, LUTS: Lower Urinary Tract Symptoms (2018)
19. Cross-Cultural Adaptation of the International Consultation Incontinence Questionnaire Male Lower Urinary Tract Symptoms—Long Form (Iciq-Mluts-Lf) in Persian, Neurourology and Urodynamics (2017)
20. The Effect of Biofeedback Versus Functional Electrical Stimulation in the Treatment of Stress Urinary Incontinence, Journal of Rehabilitation Sciences and Research (2019)