Thrombotic Microangiopathy in the Renal Allograft: Results of the Tma Banff Working Group Consensus on Pathologic Diagnostic Criteria

Thrombotic Microangiopathy in the Renal Allograft: Results of the Tma Banff Working Group Consensus on Pathologic Diagnostic Criteria Publisher Pubmed

Afrouzian M¹ ; Kozakowski N² ; Liapis H^{3, 4} ; Broecker V⁵ ; Truong L⁶ ; Avilacasado C⁷ ; Regele H² ; Seshan S⁸ ; Ambruzs JM⁹ ; Farris AB¹⁰ ; Buob D¹¹ ; Chander PN¹² ; Cheraghvandi L¹³ ; Clahsenvan Groningen MC^{14, 15} Show All Authors

Afrouzian M¹
Kozakowski N²
Liapis H^{3, 4}
Broecker V⁵
Truong L⁶
Avilacasado C⁷
Regele H²
Seshan S⁸
Ambruzs JM⁹
Farris AB¹⁰
Buob D¹¹
Chander PN¹²
Cheraghvandi L¹³
Clahsenvan Groningen MC^{14, 15}
De Almeida Araujo S¹⁶
Ertoy Baydar D¹⁷
Formby M^{18, 19}
Galesic Ljubanovic D²⁰
Herrera Hernandez L²¹
Honsova E²²
Mohamed N²³
Ozluk Y²⁴
Rabant M²⁵
Royal V²⁶
Stevenson HL¹
Toniolo MF²⁷
Taheri D²⁸

Source: Transplant International Published:2023

Abstract

The Banff community summoned the TMA Banff Working Group to develop minimum diagnostic criteria (MDC) and recommendations for renal transplant TMA (Tx-TMA) diagnosis, which currently lacks standardized criteria. Using the Delphi method for consensus generation, 23 nephropathologists (panelists) with >3 years of diagnostic experience with Tx-TMA were asked to list light, immunofluorescence, and electron microscopic, clinical and laboratory criteria and differential diagnoses for Tx-TMA. Delphi was modified to include 2 validations rounds with histological evaluation of whole slide images of 37 transplant biopsies (28 TMA and 9 non-TMA). Starting with 338 criteria in R1, MDC were narrowed down to 24 in R8 generating 18 pathological, 2 clinical, 4 laboratory criteria, and 8 differential diagnoses. The panelists reached a good level of agreement (70%) on 76% of the validated cases. For the first time in Banff classification, Delphi was used to reach consensus on MDC for Tx-TMA. Phase I of the study (pathology phase) will be used as a model for Phase II (nephrology phase) for consensus regarding clinical and laboratory criteria. Eventually in Phase III (consensus of the consensus groups) and the final MDC for Tx-TMA will be reported to the transplantation community. Copyright © 2023 Afrouzian, Kozakowski, Liapis, Broecker, Truong, Avila-Casado, Regele, Seshan, Ambruzs, Farris, Buob, Chander, Cheraghvandi, Clahsen-van Groningen, de Almeida Araujo, Ertoy Baydar, Formby, Galesic Ljubanovic, Herrera Hernandez, Honsova, Mohamed, Ozluk, Rabant, Royal, Stevenson, Toniolo and Taheri.

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Style	Citing Format
MLA	Afrouzian M, et al.. "Thrombotic Microangiopathy in the Renal Allograft: Results of the Tma Banff Working Group Consensus on Pathologic Diagnostic Criteria." Transplant International, vol. 36, no. , 2023, pp. -.
APA	Afrouzian M, Kozakowski N, Liapis H, Broecker V, Truong L, Avilacasado C, Regele H, Seshan S, Ambruzs JM, Farris AB, Buob D, Chander PN, Cheraghvandi L, Clahsenvan Groningen MC, De Almeida Araujo S, Ertoy Baydar D, Formby M, Galesic Ljubanovic D, Herrera Hernandez L, ... Taheri D (2023). Thrombotic Microangiopathy in the Renal Allograft: Results of the Tma Banff Working Group Consensus on Pathologic Diagnostic Criteria. Transplant International, 36(), -.
Chicago	Afrouzian M, Kozakowski N, Liapis H, Broecker V, Truong L, Avilacasado C, Regele H, et al.. "Thrombotic Microangiopathy in the Renal Allograft: Results of the Tma Banff Working Group Consensus on Pathologic Diagnostic Criteria." Transplant International 36, no. (2023): -.
Harvard	Afrouzian M et al. (2023) 'Thrombotic Microangiopathy in the Renal Allograft: Results of the Tma Banff Working Group Consensus on Pathologic Diagnostic Criteria', Transplant International, 36(), pp. -.
Vancouver	Afrouzian M, Kozakowski N, Liapis H, Broecker V, Truong L, Avilacasado C, et al.. Thrombotic Microangiopathy in the Renal Allograft: Results of the Tma Banff Working Group Consensus on Pathologic Diagnostic Criteria. Transplant International. 2023;36():-.
BibTex	@article{ author = {Afrouzian M and Kozakowski N and Liapis H and Broecker V and Truong L and Avilacasado C and Regele H and Seshan S and Ambruzs JM and Farris AB and Buob D and Chander PN and Cheraghvandi L and Clahsenvan Groningen MC and De Almeida Araujo S and Ertoy Baydar D and Formby M and Galesic Ljubanovic D and Herrera Hernandez L and Honsova E and Mohamed N and Ozluk Y and Rabant M and Royal V and Stevenson HL and Toniolo MF and Taheri D}, title = {Thrombotic Microangiopathy in the Renal Allograft: Results of the Tma Banff Working Group Consensus on Pathologic Diagnostic Criteria}, journal = {Transplant International}, volume = {36}, number = {}, pages = {-}, year = {2023} }
RIS	TY - JOUR AU - Afrouzian M AU - Kozakowski N AU - Liapis H AU - Broecker V AU - Truong L AU - Avilacasado C AU - Regele H AU - Seshan S AU - Ambruzs JM AU - Farris AB AU - Buob D AU - Chander PN AU - Cheraghvandi L AU - Clahsenvan Groningen MC AU - De Almeida Araujo S AU - Ertoy Baydar D AU - Formby M AU - Galesic Ljubanovic D AU - Herrera Hernandez L AU - Honsova E AU - Mohamed N AU - Ozluk Y AU - Rabant M AU - Royal V AU - Stevenson HL AU - Toniolo MF AU - Taheri D TI - Thrombotic Microangiopathy in the Renal Allograft: Results of the Tma Banff Working Group Consensus on Pathologic Diagnostic Criteria JO - Transplant International VL - 36 IS - SP - EP - PY - 2023 ER -

Style

Citing Format

MLA

Afrouzian M, et al.. "Thrombotic Microangiopathy in the Renal Allograft: Results of the Tma Banff Working Group Consensus on Pathologic Diagnostic Criteria." Transplant International, vol. 36, no. , 2023, pp. -.

APA

Afrouzian M, Kozakowski N, Liapis H, Broecker V, Truong L, Avilacasado C, Regele H, Seshan S, Ambruzs JM, Farris AB, Buob D, Chander PN, Cheraghvandi L, Clahsenvan Groningen MC, De Almeida Araujo S, Ertoy Baydar D, Formby M, Galesic Ljubanovic D, Herrera Hernandez L, ... Taheri D (2023). Thrombotic Microangiopathy in the Renal Allograft: Results of the Tma Banff Working Group Consensus on Pathologic Diagnostic Criteria. Transplant International, 36(), -.

Chicago

Afrouzian M, Kozakowski N, Liapis H, Broecker V, Truong L, Avilacasado C, Regele H, et al.. "Thrombotic Microangiopathy in the Renal Allograft: Results of the Tma Banff Working Group Consensus on Pathologic Diagnostic Criteria." Transplant International 36, no. (2023): -.

Harvard

Afrouzian M et al. (2023) 'Thrombotic Microangiopathy in the Renal Allograft: Results of the Tma Banff Working Group Consensus on Pathologic Diagnostic Criteria', Transplant International, 36(), pp. -.

Vancouver

Afrouzian M, Kozakowski N, Liapis H, Broecker V, Truong L, Avilacasado C, et al.. Thrombotic Microangiopathy in the Renal Allograft: Results of the Tma Banff Working Group Consensus on Pathologic Diagnostic Criteria. Transplant International. 2023;36():-.

BibTex

@article{ author = {Afrouzian M and Kozakowski N and Liapis H and Broecker V and Truong L and Avilacasado C and Regele H and Seshan S and Ambruzs JM and Farris AB and Buob D and Chander PN and Cheraghvandi L and Clahsenvan Groningen MC and De Almeida Araujo S and Ertoy Baydar D and Formby M and Galesic Ljubanovic D and Herrera Hernandez L and Honsova E and Mohamed N and Ozluk Y and Rabant M and Royal V and Stevenson HL and Toniolo MF and Taheri D}, title = {Thrombotic Microangiopathy in the Renal Allograft: Results of the Tma Banff Working Group Consensus on Pathologic Diagnostic Criteria}, journal = {Transplant International}, volume = {36}, number = {}, pages = {-}, year = {2023} }

RIS

TY - JOUR
AU - Afrouzian M
AU - Kozakowski N
AU - Liapis H
AU - Broecker V
AU - Truong L
AU - Avilacasado C
AU - Regele H
AU - Seshan S
AU - Ambruzs JM
AU - Farris AB
AU - Buob D
AU - Chander PN
AU - Cheraghvandi L
AU - Clahsenvan Groningen MC
AU - De Almeida Araujo S
AU - Ertoy Baydar D
AU - Formby M
AU - Galesic Ljubanovic D
AU - Herrera Hernandez L
AU - Honsova E
AU - Mohamed N
AU - Ozluk Y
AU - Rabant M
AU - Royal V
AU - Stevenson HL
AU - Toniolo MF
AU - Taheri D
TI - Thrombotic Microangiopathy in the Renal Allograft: Results of the Tma Banff Working Group Consensus on Pathologic Diagnostic Criteria
JO - Transplant International
VL - 36
IS -
SP -
EP -
PY - 2023
ER -

Science Communicator Platform

Authors

Abstract