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A Simple Sore Can Lead to Limb Amputation; Metastatic Squamous Cell Carcinoma of the Sole in a 22-Year-Old Man Publisher



Faraji N1 ; Pourbahram R2 ; Goli R1 ; Parvaresh B3 ; Alidoust H4 ; Dastgerdi ME5
Authors

Source: International Journal of Surgery Case Reports Published:2024


Abstract

Introduction and importance: Squamous cell carcinoma (SCC) is a cancerous tumor that can develop when normal keratinocytes undergo a transformation into invasive cancer cells, typically due to genetic mutations that affect cell growth and differentiation. SCC is frequently found on sun-exposed areas of the skin like the face, ears, neck, and hands, but it is unusual to see it develop on the soles of the feet. Case report: This case is about a 22-year-old man who came in with a persistent sore on the bottom of his left foot. The patient mentioned sustaining a small injury to his foot about two weeks before seeking medical help, which started off as a minor wound but deteriorated over time. Ultimately, the diagnosis revealed squamous cell carcinoma that had spread to the lungs and lymph nodes. Discussion: This case highlights the importance of considering the possibility of malignancy in non-healing wounds, even in young patients without known risk factors. The initial presentation of a simple sore that progressed to metastatic SCC underscores the challenges in diagnosing and managing skin cancers in atypical presentations. Conclusion: This case highlights cancer's aggressiveness and atypical youth presentations, stressing early detection, aggressive treatment, and comprehensive patient support. Continued research is crucial for enhancing disease management. © 2024 The Author(s)
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2. Aggressive and Neglected Basal Cell Carcinoma., Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] (2005)
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