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A Case of Intracranial Malignant Fibrous Histiocytoma



Sarrami AH1 ; Setareh M2, 4 ; Afsharmoghaddam N3 ; Izadinejad M2, 4 ; Saadatnia M5
Authors
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Authors Affiliations
  1. 1. School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Legal Medicine Center of Isfahan, Isfahan, Iran
  3. 3. Department of Pathology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  4. 4. Legal Medicine Center of Isfahan, Isfahan, Iran
  5. 5. Isfahan Neurosciences Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Journal of Research in Medical Sciences Published:2011

Abstract

We describe a case of intracranial malignant fibrous histiocytoma which had infiltrated pons, cerebellum and basal surface of left temporal lobe without any visible mass. The patient presented with a sudden loss of consciousness and vomiting. Clinical findings, laboratory tests, imaging and examination of the cerebrospinal fluid tended to establish the diagnosis of an infectious condition than a malignancy. Without any response to the antibiotics and with a progressive deterioration of neurologic and mental condition, the patient died after 20 days. In the autopsy, histological and immunohistochemical study of the brain revealed the diagnosis of malignant fibrous histiocytoma (MFH).