A Narrative Review on the Role of Polycystic Ovary Syndrome in the Increasing of Cervical Incompetence in Pregnant Women; [مروری روایی بر نقش سندرم تخمدان پلی‌کیستیک در افزایش نارسایی دهانه رحم در زنان باردار] Publisher



Mobini FZ ; Memar F
Source: Iranian Journal of Obstetrics, Gynecology and Infertility Published:2025

Abstract

Introduction: Cervical Incompetence (CI), one of the major causes of miscarriage, preterm labor, and Polycystic Ovary Syndrome (PCOS), is a chronic endocrine disorder and the most common cause of anovulatory infertility. The present review study was conducted with aim to determine the role of PCOS in increasing the risk of CI in pregnant women. Methods: In this review study, to find the related articles, a comprehensive search was conducted in Web of Science, SID, Scopus, and PubMed databases without any time limitation using English keywords of Polycystic Ovary Syndrome, Uterine Cervical Incompetence, Incompetent Cervices, and Persian keywords. Original articles with relevant content and full text were included in the study. The Strobe and Consort checklists were used to evaluate the studies. Results: In total, 13 eligible articles out of 1276 articles were selected for this study. According to the results of the studies, 8 articles indicate that the prevalence of CI during pregnancy is higher in individuals with PCOS. Elevated androgen levels, higher serum relaxin levels, and the use of assisted reproductive technologies are the associated factors of the higher prevalence of CI during pregnancy in PCOS women. Conclusion: Based on the evidence, PCOS is associated with an increased risk of CI during pregnancy. Therefore, more precise cervical screening and monitoring is recommended in pregnant women with PCOS to prevent complications such as preterm birth and miscarriage. © 2025, Mashhad University of Medical Sciences. All Rights reserved.