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Transplant and Kidney Repair



Guitynavard F1 ; Aghamir SMK1 ; Taheri D2
Authors
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Authors Affiliations
  1. 1. Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Pathology, Isfahan Kidney Diseases Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Stem Cells in Urology Published:2020

Abstract

Kidney injury including acute and chronic types will end in transient or permanent renal failure. Even patients with an episode of acute kidney injury are at a higher risk of developing chronic kidney injury in future. Stem cells have an interesting ability to migrate into an injured tissue and repair it via different mechanisms. So, stem cell therapy can be a novel alternative of different current treatment for renal failure such as hemodialysis and kidney transplant. In addition, by immunoregulatory mechanisms stem cells can improve graft survival in kidney transplantation. In this chapter we aim to present a summary on the stem cells application in various kidney diseases as well as in kidney transplant. © Springer Nature Switzerland AG 2020.
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