Production of Chlorogenic Acid in Varthemia Persica Dc (Var. Persica) Callus Cultures

Production of Chlorogenic Acid in Varthemia Persica Dc (Var. Persica) Callus Cultures

Siahpoush A¹ ; Ghasemi N² ; Shams Ardakani M³ ; Asghari G⁴

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1. Department of Pharmacognosy, Faculty of Pharmacy, Jondishapoor University of Medical Sciences, Ahvaz, Iran
2. Department of Pharmacognosy, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran
3. Department of Pharmacognosy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
4. Isfahan Pharmaceutical Sciences Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Research in Pharmaceutical Sciences Published:2011

Abstract

Chlorogenic acid, a pharmacologically important compound, is a phenolic compound that occurs in certain commonly used medicinal herbs. We looked for the presence of this compound in the callus cultures of Varthemia persica DC (var. persica). We have evaluated the conditions for establishment of callus cultures of V. persica and the in vitro production of chlorogenic acid. Callus was initiated by culturing seedling of V. persica on MS basal medium supplemented with different concentrations of kinetin, naphthalene acetic acid and 2,4-diphenoxy acetic acid. Also, the influence of light, and phytohormones on the production of chlorogenic acid was examined. Kinetin stimulated the production of chlorogenic acid. Replacement of 2,4-diphenoxy acetic acid with naphthalene acetic acid did not alter the chlorogenic acid production. The ability to induce the accumulation of chlorogenic acid in the V. persica callus cultures offers an opportunity to produce a phenolic compound with therapeutic value.

2. Production of Rosmarinic Acid in Echium Amoenum Fisch. and C.A. Mey. Cell Cultures, Iranian Journal of Pharmaceutical Research (2005)

3. Stereospecific Biotransformation of (±) Phenylethyl Propionate by Cell Cultures of Peganum Harmala L., Iranian Biomedical Journal (2002)

4. Influence of Salicylic Acid on Atropine Production in Datura Metel L. Callus Cultures, Pharmaceutical Sciences (2010)

Experts (# of related papers)

Gholamreza Asghari (2)

Style	Citing Format
MLA	Siahpoush A, et al.. "Production of Chlorogenic Acid in Varthemia Persica Dc (Var. Persica) Callus Cultures." Research in Pharmaceutical Sciences, vol. 6, no. 1, 2011, pp. -.
APA	Siahpoush A, Ghasemi N, Shams Ardakani M, Asghari G (2011). Production of Chlorogenic Acid in Varthemia Persica Dc (Var. Persica) Callus Cultures. Research in Pharmaceutical Sciences, 6(1), -.
Chicago	Siahpoush A, Ghasemi N, Shams Ardakani M, Asghari G. "Production of Chlorogenic Acid in Varthemia Persica Dc (Var. Persica) Callus Cultures." Research in Pharmaceutical Sciences 6, no. 1 (2011): -.
Harvard	Siahpoush A et al. (2011) 'Production of Chlorogenic Acid in Varthemia Persica Dc (Var. Persica) Callus Cultures', Research in Pharmaceutical Sciences, 6(1), pp. -.
Vancouver	Siahpoush A, Ghasemi N, Shams Ardakani M, Asghari G. Production of Chlorogenic Acid in Varthemia Persica Dc (Var. Persica) Callus Cultures. Research in Pharmaceutical Sciences. 2011;6(1):-.
BibTex	@article{ author = {Siahpoush A and Ghasemi N and Shams Ardakani M and Asghari G}, title = {Production of Chlorogenic Acid in Varthemia Persica Dc (Var. Persica) Callus Cultures}, journal = {Research in Pharmaceutical Sciences}, volume = {6}, number = {1}, pages = {-}, year = {2011} }
RIS	TY - JOUR AU - Siahpoush A AU - Ghasemi N AU - Shams Ardakani M AU - Asghari G TI - Production of Chlorogenic Acid in Varthemia Persica Dc (Var. Persica) Callus Cultures JO - Research in Pharmaceutical Sciences VL - 6 IS - 1 SP - EP - PY - 2011 ER -

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