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The Effect of 8 Week of Aerobic Exercise on Heart Cells Specific Biochemical Indicators in Women With Type 2 Diabetes Mellitus: A Randomized Clinical Trial Publisher



Amininajafabadi B1 ; Keshavarz S2 ; Asgary S3 ; Azarbarzin M4
Authors
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Authors Affiliations
  1. 1. Department of Physical Education and Sports Sciences, Najafabad Branch, Islamic Azad University, Najafabad, Iran
  2. 2. Sport Medicine Research Center, Najafabad Branch, Islamic Azad University, Najafabad, Iran
  3. 3. Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
  4. 4. Nursing and Midwifery Sciences Development Research Center, Najafabad Branch, Islamic Azad University, Najafabad, Iran

Source: Journal of Isfahan Medical School Published:2021


Abstract

Background: The aim of this study was to investigate the effect of aerobic exercise on heart cells specific biochemical indicators in women with type 2 diabetes mellitus. Methods: This randomized clinical trial study was performed on 30 women with type 2 diabetes mellitus randomly divided into experimental and control groups. The experimental group participated in an increasing aerobic exercise (running) for eight weeks, three sessions per week [55% to 75% of maximum heart rate and rating perceived exertion (RPE) of 12 to 13]. Blood samples were taken before and after the protocol. The enzyme-linked immunosorbent assay (ELISA) and enzymatic method were used to measure the variables. Findings: Troponin I decreased significantly 6 hours after the last training session in the experimental group compared to 6 hours after the last training session in the control group (P = 0.001). There was no significant difference in troponin I, 6 hours after the first training session in the experimental group compared to 6 hours after the first training session in the control group (P = 0.983). Creatine kinase-MB (CK-MB) values significantly increased in both groups; this increase was higher in the experimental group than the control group (P = 0.001). Conclusion: The results showed that the training instructions significantly decreased troponin I despite the increase in CPK-MB, which may be due to the nature of training and muscle damage during training. This can confirm the protective nature of this exercise protocol for heart tissue against the injury in women with type 2 diabetes mellitus. © 2021 Isfahan University of Medical Sciences(IUMS). All rights reserved.
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