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Yolk Sac Tumor of the Vagina Pubmed



Mahzouni P1 ; Pejhan S1 ; Ashrafi M2
Authors
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Authors Affiliations
  1. 1. Department of Pathology, Alzahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Department of Pediatric Surgery, Alzabra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Saudi Medical Journal Published:2007


Abstract

Malignant germ-cell tumors GCT are rare tumors of childhood accounting for less than 3% of pediatric malignancies. Endodermal sinus tumors EST form the most common histologic subtype of malignant GCT. The vagina is an extremely rare site for GCTs. An 8-month-old female was admitted with a short history of vaginal bleeding, and a mass protruding from the vagina. A mass was palpable anteriorly on rectal examination. Computed tomography showed a tumor mass posterior to the bladder. A biopsy revealed a vaginal EST. The serum alpha-fetoprotein was elevated. Vaginohysterectomy was carried out. She was subsequently referred to the oncologist for further management.
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