Effect of a Clinically Feasible Repeated Potassium Iodide Application Protocol on Silver Diamine Fluoride-Induced Discoloration Publisher

Summary: Can tooth darkening after silver diamine fluoride be reduced? A lab study on primary teeth found repeated potassium iodide applications limited staining. #PediatricDentistry #OralHealth

Hajiahmadi M ; Sadighbatha S
Source: European Oral Research Published:2026

Abstract

Purpose The aim is to evaluate and compare the effects of single versus repeated applications of potassium iodide (KI) on SDF-induced discoloration in primary canines. Materials and Methods Thirty-six extracted human primary canines with dentinal caries were randomly allocated into three groups: Group I received 38% SDF alone; Group II received SDF followed by a single KI application; and Group III received SDF followed by immediately application after SDF and repeated on days 1,3, and 5. Color change (ΔΕ) was assessed on Days 1, 14, and30 using a spectrophotometer based on the CIE Lab* system.StatisticalanalysisincludedOne-WayANOVAwithTukeyposthoctestsfor between-group comparisons, and Repeated Measures ANOVA with Bonferroni adjustment for within-group comparisons. Results All groups showed significant differences in ΔΕ values at each time point, except between the single and repeated KI groups on Day 1. The Group I exhibited the highest ΔΕ values throughout the study, indicating the greatest discoloration, while Group III resulted in the lowest values. Over time, a progressive increase in discoloration was observed in Groups II, whereas partial color stability was maintained in Group III. Conclusion Repeated application of KI after SDF treatment can result in a higherr eductionin tooth discoloration compared to a single-application. This protocol may enhance the clinical acceptability of SDF, especiallyforvisible anterior teeth in pediatric patients. © (2026), (Istanbul University Press). All right reserved.