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Antioxidant Activities of Juniperus Foetidissima Essential Oils Against Several Oxidative Systems Publisher



Emami SA1 ; Asgary S2 ; Naderi GA2 ; Shams Ardekani MR3 ; Kasher T4 ; Aslani S4 ; Airin A4 ; Sahebkar A5
Authors
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Authors Affiliations
  1. 1. Department of Pharmacognosy, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
  2. 2. Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Iran
  3. 3. Department of Pharmacognosy, School of Pharmacy, Tehran University of Medical Sciences, Iran
  4. 4. School of Pharmacy, Isfahan University of Medical Sciences, Iran
  5. 5. Biotechnology Research Center and School of Pharmacy, Mashhad University of Medical Sciences, Iran

Source: Revista Brasileira de Farmacognosia Published:2011


Abstract

The present study aimed to evaluate the antioxidant activity of essential oils obtained from branchlets of male and female trees as well as fruits of Juniperus foetidissima Willd., Cupressaceae, from Iran. For this purpose,essential oils of J. foetidissima were phytochemically analyzed and different concentrations of them were tested in five oxidative systems: 1) low-density lipoprotein oxidation; 2) linoleic acid peroxidation; 3) red blood cell hemolysis; 4) hemoglobin glycation; and 5) insulin glycation assays. In all employed systems, antioxidant effects were observed from the three tested oils though in varying degrees. The most promising activities of the oils were observed against hemoglobin and insulin glycation. Antioxidant activities of the oilsdid not appear to be dose-dependent. In addition, no consistent superiority in antioxidant effects was observed from a single oil in different assays. In view of the current results, J. foetidissima branchlet and fruit oils could be regarded as effective natural products with anti-glycation activity.
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